Application Note

Testing Oxygen Permeation Of Capsule Seals

Source: MOCON, Inc.

Capsules such as those used in pharmaceutical products are critical in ensuring the shelf life of the medications they contain. Many of the next generation of pharmaceutical drugs are highly oxygen-sensitive, so a capsule that allows too much oxygen to permeate in will decrease their shelf life and make them unsafe or ineffective. Therefore, it is essential to test both the material used to make these capsules as well as the finished capsules to ensure that the oxygen transmission rate (OTR) is within the desired limit.

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