toxSYS
TOXSYS is a continuity product, with major new topics, subject areas, and analysis routines added semi-annually in various areas of environmental health and science. The core of the information system contains a wealth of toxicological information on over 230,000 compounds, with exhaustive literature references on these compounds, as well as a compendium of data on a variety of toxic effects, such as toxicity, carcinogenicity, mutagenicity, and chronic effects. All data is structured for ease of access. In addition, a large endocrine disruptor sub-database gives exhaustive results on a wide range of studies on the effects of these disruptors.
TOXSYS Features
- Query driven Boolean searches for selected topics, compounds, authors, and abstracts.
- Interactive graphical display in 2D or 3D of toxicity/ mutagenic/carcinogenic effects, compound properties (e.g., LogP), and 3D structure representations.
- Compound searches by chemical formula, chemical structure, CAS number, molecular weight, substructure, or compound similarity.
- Toxic assessment of compounds, using a unique, built-in neural net analysis to predict potential toxicity of compounds. LD50 predictions, with similarity searching, to assess the degree of validity of the predictive models, as well as substructure contributions to toxicity.
- Integrated drawing and information retrieval: draw a 2D structure, pull up all information on the compound, or run a similarity search to find comparable compounds.
- Integration with QSARIS, makes it easy to construct QSAR models from data in TOXSYS
SciVision, 200 Wheeler Road, Burlington, MA 01803. Tel: 781-272-4949; Fax: 781-272-6868.