Case Study: UF/DF Systems

By Integrated Process Engineers & Constructors Inc. (IPEC)

Product is supplied to the UF/DF vessel from a Chromatography System and concentrated. When the target volume in the vessel is reached, the media is exchanged with a buffer through diafiltration. A control valve on the retentate side of the filters maintains a desired trans-membrane pressure (TMP). A control valve on the permeate side of the membrane maintains a desired permeate flowrate. The control valves control TMP and permeate flow throughout processing and membrane preparation.