Unleashing The Potential For Polyvinyl Alcohol In Spray Drying For Oral Solid Dosage Forms
During the development of oral solid dosage forms, pharmaceutical scientists are increasingly encountering complex formulation challenges, particularly those related to the instability and low solubility of active pharmaceutical ingredients (APIs). These issues can significantly hinder the effectiveness and manufacturability of drug products. Polyvinyl alcohol (PVA), due to its versatile functional properties, has emerged as a promising excipient capable of addressing many of these formulation hurdles. Its unique characteristics make it especially suitable for advanced drug delivery techniques such as spray drying. Recent data and case studies have demonstrated the effectiveness of PVA in spray drying applications across a diverse array of model APIs. These include not only conventional small molecules but also newer, more complex therapeutic agents, such as PROTACs (proteolysis-targeting chimeras), which represent a groundbreaking class of drugs with significant therapeutic potential. This webinar offers in-depth technical insights into the application of PVA in pharmaceutical formulations and explores how PVA can be leveraged to support a broad spectrum of APIs.
Gain a deeper understanding of how this multifunctional polymer can be a game-changer in overcoming formulation challenges and advancing drug development.
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