Case Study

Using Common Low Moisture Fillers In The Roller Compacted Tablets

Source: Metrics Contract Services

By Anshul Gupte, Charles Reynolds, Jerry Mizell, Russell Branch, Brian Warren, Wayne Jefferson, and Brad Gold

The aim of this study was to compare the benefit of using common low moisture grade pharmaceutical excipients: Mannitol, NF (Grades: Pearlitol® 300 DC, Pearlitol® 160c) (Roquette) and/or Microcrystalline Cellulose, NF (Grades: Avicel® PH-­‐200 LM, Avicel ® PH 112) (FMC Corp.) as fillers in a tablet formulation to limit the moisture uptake by a model hygroscopic drug manufactured with a roller compaction process.

access the Case Study!

Get unlimited access to:
Trend and Thought Leadership Articles
Case Studies & White Papers
Extensive Product Database
Members-Only Premium Content
Welcome Back! Please Log In to Continue. X

Enter your credentials below to log in. Not yet a member of Pharmaceutical Online? Subscribe today.

Subscribe to Pharmaceutical Online X

Please enter your email address and create a password to access the full content, Or log in to your account to continue.

or

Subscribe to Pharmaceutical Online

Please tell us more about you so that we can customize our newsletters to your specific interests: