Why And How To Replace Dye Ingress Test By Deterministic CCIT Methods?

Repeatable and proper container closure integrity testing of primary packaging is essential to ensure quality and effectiveness of pharmaceutical products. Blue dye test and microbial ingress are mainly used for decades. Recently, guidelines provided by regulatory organizations like USP 1207 or Annex 1 request statistical analysis and push for use of deterministic and non-destructive methods.

In this webinar we will help you understand the challenges and limitations of the blue dye test and compare the sensitivity of blue dye test to other methods based on a comprehensive study.

• How is the blue dye working (parameters, limits, etc.)
• Sensitivity of blue dye vs. defect geometry
• Comparative study with Optical Emission Spectroscopy, Mass Extraction and Helium
• Select the right method to replace your blue dye