With more than 60 years of experience in formulation of quality aqueous cleaners, Alconox, Inc. understands the cleaning needs of the pharmaceutical industry, including stringent FDA regulations and GMP compliance. Pharmaceutical processing professionals need safe, effective, and easy to validate cleaners for manual, machine wash, and clean-in-place applications for removing difficult to clean residues like titanium dioxide, petrolatum, and tablet coating residues.
Alconox, Inc. has a range of 12 products, which vary from high emulsifying to low foaming and powder to liquid. Alconox aqueous cleaners are ideal for a variety of cleaning applications including ultrasonic, clean in place, machine, and parts washer.
The experts at Alconox formulate all cleaners to be biodegradeable, readily disposable, and free rinsing to leave no interfering residues.
Sizes range from single gallon and four-pound boxes to drums, ideal for scaling from the research and development stage to large-scale manufacturing.
All cleaner brands are GMP compliant and have lot specific COA, technical bulletins, and material safety data sheets.
Alconox brands are manufactured in the United States and are sold through leading distributors in the laboratory, healthcare, and industrial fields in more than 40 countries.
Keylajet is a low-foaming high alkaline liquid designed for hard to clean soils, grit, grime, slime, grease, buffing compounds, oils, particulates, deposits, chemical and solvents, mold releases, metal oxides, and more.
Pharmaceutical and Biotechnology processing equipment can be made residue-free clean with Alconox Critical Cleaning Detergents. Alconox, Inc. detergents are available worldwide with consistent formulations, certificates of analysis, ingredient toxicity data, shelf life information, residue sampling techniques, ingredients disclosure, analytic methods, lot number tracking, and validation support.
Solujet cleaner is the detergent to consider for your next new pharmaceutical cleaning project. Unlike a leading CIP cleaner, Solujet has high wetting surfactants that enhance emulsifying, wetting, dispersing and rinsing. The surfactants allow faster, more efficient cleaning and easier rinsing.
Medical device cleaning by definition requires critical cleaning for use in demanding human health and veterinary applications.
Alconox lab detergents leave no interfering residues on laboratory equipment. Since 1946, Alconox, Inc. has provided quality laboratory glassware cleaner, residue-free cleaners to meet the demanding needs of laboratory professionals.
Effective sterilization requires effective cleaning - and when it comes to cleaning reusable instruments and equipment, Alconox detergents meet the most demanding healthcare and hospital cleaning criteria.
Alconox cosmetic cleaners make short work of silicon, titanium dioxide, and other hard-to-clean residues.
From spinner flasks to production fermentation tanks, Alconox detergents can eliminate cross-contamination and assure reliably clean equipment for all of your biotechnology cleaning needs.
Alconox, Inc. provides a range of validation information to help support the company's brands.
Concentrated to save money. Phosphate-free, biodegradable, and readily disposable. Low-foaming, high-wetting detergent for maximum performance. Free rinsing to give users reliable results and no interfering residues. Ideal for clean-in-place (CIP) cleaning and floor-standing lab washing machines.
Low foaming acid cleaner and rinse for high performance results from your cleaning machinery. Use to pass your cleaning validation tests for lab accreditation and plant inspection approval.
Concentrated to save money, this detergent replaces corrosive acids and hazardous solvents. It’s phosphate-free, biodegradable, readily disposable, and is free-rinsing to give reliable results and no interfering residues.
Concentrated to save money. Phosphate free, biodegradable and readily disposable. Penetrating wetting power to save time. Free rinsing to give reliable results and no interfering residues.
Concentrated to save you money. Phosphate-free, biodegradable, and readily disposable. Low foaming heavy duty detergent for high performance results. Free rinsing to give you reliable results and no interfering residues. Ideal for under-counter and floor standing lab washing machines.
Concentrated to save you money. Biodegradable and readily disposable. Non-ionic, low foaming cleaner for high performance from your cleaning machinery without damaging washer parts. Free rinsing to give you reliable results and no interfering residues. Use to pass your cleaning validation tests for lab accreditation and plant inspection approval.
Concentrated, biodegradable, and disposable, this low-foaming heavy-duty detergent provides high-performance results for cleaning machinery. Use it to pass your cleaning validation tests for lab accreditation and plant inspection approval.
Concentrated to save you money. Biodegradable and readily disposable. Penetrating wetting power to save you time. Replaces corrosive acids and hazardous solvents. Free rinsing to give you reliable results and no interfering residues. Use to pass your cleaning validation tests for lab accreditation and plant inspection approval.
Low foaming for use in mechanical and spray washers. Neutral pH for non-corrosive cleaning, safe handling, and easy waste disposal. No chelation or alkalinity waste treatment problems. Concentrated for economical use. Free rinsing to eliminate interfering residues. Biodegradable and phosphate free.
Detergent 8 is concentrated to save you money, biodegradable, and readily disposable. Its penetrating wetting power saves you time. It’s free rinsing to give you reliable results and no interfering residues.
Alconox, Inc.
30 Glenn St., Suite 309
White Plains, NY 10603
UNITED STATES
Phone: 914-948-4040
Fax: 914-948-4088
Contact: Jeff Phillips
The principal concern for any scientist or technician working in the laboratory is that glassware, instruments, and equipment be free of interfering residues.
The use of aqueous cleaning in medical device manufacturing can provide numerous benefits in terms of efficacy, minimal surface contact and reduced residue potential, and easier cleaning validation.
Getting the best results from any cleaner requires proper mixing and cleaning procedures. This article includes mixing directions for aqueous cleaning detergent and methods for monitoring performance.
The use of aqueous cleaning in pharmaceutical manufacturing can provide numerous benefits in terms of efficacy, minimal surface contact, reduced residue potential, and easier cleaning validation.
Cleaning validation or verification is a necessary regulatory compliance step in medical device manufacturing and reprocessing. Support from the cleaner manufacturer can save time and money.
Cleaning validation is a necessary and time-consuming part of manufacturing pharmaceuticals. The validation process can be expedited and cost reduced if the cleaner supplier can provide support.
Alconox, Inc. is dedicated to being the leader in critical cleaning detergents. We manufacture quality detergents made in the United States and provide outstanding technical service to the scientists and engineers with precision cleaning needs.
For cleanroom cleaning, users should consider liquid concentrate detergents to avoid the creation of powdered clouds in the classified environment.
Q. What does free rinsing detergent mean?
A faster and more efficient method to remove silicone grease from syringes is to use very hot water for cleaning and very hot water for rinsing.
It is very important to pay attention to how glassware and equipment is loaded in to a washer so as to minimize trapping any water from cycle to cycle.
Q. What kind of cleaner options can you provide which can be safely be used in stainless steel dishwashers?
Q. We are interested in Alconox® detergent for cleaning during our production process. Since we produce several kinds of medicine, we need to be sure Alconox® do not leave any residue after cleaning. We want to test the residue of Alconox® by UV method or HPLC method. Could you send reference or guide on these methods?
Q. Can I use pH paper to confirm cleaning and rinsing of labware to comply with lab accreditation requirements?
Dissolved oxygen and pH probes used in fermentation vessels can get develop buildup from the fermentation media that degrades the probe performance and increases the likelihood of contamination.
As a rule of thumb, alkaline detergents are best for organic, oily residues, while acidic detergents are best for inorganic residue like salts and oxides.
When beginning cleaning validation, a company must identify the residues to be tested and then select the best detection method.
Nanotechnology is currently employed across a wide range of industrial, research, and academic applications. Stringent cleaning protocols are essential to the successful fabrication of nanotechnology particles, structures, and systems.
The following test procedures are suitable for detecting detergent residues resulting from improper rinsing and can be used to meet laboratory accreditation guidelines and questionnaires such as the College of American Pathologist program of State water lab accreditation programs.
A great deal is known about how pH affects aqueous critical cleaning. Typically, alkaline cleaners are used on oily residues and acidic cleaners are used on inorganic residues.
Typically pharmaceutical operations require transition from bench scale R&D to pilot studies to full-scale manufacturing.
Today's aqueous critical-cleaning detergents are blended for specific applications. Substrate, degree of soil load, and cleaning processes are all important considerations when selecting a detergent.
Cleaning validation is a necessary and time consuming part of manufacturing pharmaceuticals. The validation process can be expedited and cost of validation can be lowered if the cleaner supplier can provide support, allowing for pharmaceuticals to get to market faster and at a lower cost. This paper outlines the basics of cleaning validation, as well as discussing the kinds of support services you should seek from your supplier of critical cleaning products in order to optimize your cleaning validation process. By Malcolm McLaughlin
The benefits of employing aqueous cleaning in pharmaceutical manufacturing are numerous. Virtually any pharmaceutical manufacturing equipment from tablet press to a stainless steel mixing tank can achieve their defined critically clean criteria using aqueous cleaning. Typically aqueous cleaners are formulated to ensure maximal cleaning performance by using key ingredients such as surface active agents (surfactants) that are excellent wetting agents that allow the cleaning solution to penetrate into crevices while getting under soils to allow for removal. Often very dilute solutions of aqueous cleaner effectively removes even worst case substances off a variety of hard surfaces including stainless steel, glass, plastic, or porcelain. By Malcolm McLaughlin
The principal concern for any scientist or technician working in the laboratory is that glassware, instruments, and equipment be free of interfering residues.
