About Alconox

With more than 60 years of experience in formulation of quality aqueous cleaners, Alconox, Inc. understands the cleaning needs of the pharmaceutical industry, including stringent FDA regulations and GMP compliance. Pharmaceutical processing professionals need safe, effective, and easy to validate cleaners for manual, machine wash, and clean-in-place applications for removing difficult to clean residues like titanium dioxide, petrolatum, and tablet coating residues.

Alconox Products

Alconox, Inc. has a range of 12 products, which vary from high emulsifying to low foaming and powder to liquid. Alconox aqueous cleaners are ideal for a variety of cleaning applications including ultrasonic, clean in place, machine, and parts washer.

The experts at Alconox formulate all cleaners to be biodegradeable, readily disposable, and free rinsing to leave no interfering residues.

Sizes range from single gallon and four-pound boxes to drums, ideal for scaling from the research and development stage to large-scale manufacturing.

All cleaner brands are GMP compliant and have lot specific COA, technical bulletins, and material safety data sheets.

Alconox brands are manufactured in the United States and are sold through leading distributors in the laboratory, healthcare, and industrial fields in more than 40 countries.

AQUEOUS CLEANING PRODUCTS

Cleaning Detergent: Low-Foaming, High-Alkaline Liquid Cleaning Detergent: Low-Foaming, High-Alkaline Liquid

Keylajet is a low-foaming high alkaline liquid designed for hard to clean soils, grit, grime, slime, grease, buffing compounds, oils, particulates, deposits, chemical and solvents, mold releases, metal oxides, and more.

Cleaning Pharm & Biotech Processing Equipment Cleaning Pharm & Biotech Processing Equipment

Pharmaceutical and Biotechnology processing equipment can be made residue-free clean with Alconox Critical Cleaning Detergents. Alconox, Inc. detergents are available worldwide with consistent formulations, certificates of analysis, ingredient toxicity data, shelf life information, residue sampling techniques, ingredients disclosure, analytic methods, lot number tracking, and validation support.

Cleaning Detergent For The Life Sciences Industry Cleaning Detergent For The Life Sciences Industry

Solujet cleaner is the detergent to consider for your next new pharmaceutical cleaning project. Unlike a leading CIP cleaner, Solujet has high wetting surfactants that enhance emulsifying, wetting, dispersing and rinsing.  The surfactants allow faster, more efficient cleaning and easier rinsing.

Medical Device Cleaning Detergents Medical Device Cleaning Detergents

Medical device cleaning by definition requires critical cleaning for use in demanding human health and veterinary applications.

Laboratory Cleaning Detergents Laboratory Cleaning Detergents

Alconox lab detergents leave no interfering residues on laboratory equipment. Since 1946, Alconox, Inc. has provided quality laboratory glassware cleaner, residue-free cleaners to meet the demanding needs of laboratory professionals.

Healthcare Cleaning Detergents Healthcare Cleaning Detergents

Effective sterilization requires effective cleaning - and when it comes to cleaning reusable instruments and equipment, Alconox detergents meet the most demanding healthcare and hospital cleaning criteria.

Cosmetic Manufacturing Cleaning Detergents Cosmetic Manufacturing Cleaning Detergents

Alconox cosmetic cleaners make short work of silicon, titanium dioxide, and other hard-to-clean residues.

Biopharmaceutical Cleaning Validation Biopharmaceutical Cleaning Validation

From spinner flasks to production fermentation tanks, Alconox detergents can eliminate cross-contamination and assure reliably clean equipment for all of your biotechnology cleaning needs.

Cleaning Validation Methods Cleaning Validation Methods
Alconox, Inc. has a range of 12 products, which vary from high emulsifying to low foaming and powder to liquid. Alconox aqueous cleaners are ideal for a variety of cleaning applications including ultrasonic, clean in place, machine, and parts washer.
Cleaning Validation (21 CFR Part 211.67) Cleaning Validation (21 CFR Part 211.67)
Alconox, Inc. can assist you in selecting an appropriate cleaner for cleaning pharmaceutical manufacturing equipment and utensils to prevent malfunctions or contamination that would alter the safety, identity, strength, quality or purity of the drug product beyond the official or other established requirements.
Cleaning Validation References Cleaning Validation References

Alconox, Inc. provides a range of validation information to help support the company's brands.

Clean In Place Clean In Place
With typical use for pipe, tank, and filtration systems, Alconox offers a range of products to assure clean systems without disassembly.
Ultrasonic Cleaning Ultrasonic Cleaning
Alconox ultrasonic cleaning products clean large batches of articles and provide fast, effective, penetrating, and convenient cleaning.
Manual Cleaning Manual Cleaning
Use Alconox manual cleaning products for cleaning small articles such as medical examination instruments, labware, or circuit boards, and large articles such as process equipment.
Low-Foaming, Phosphate-Free Liquid Detergent Low-Foaming, Phosphate-Free Liquid Detergent

Concentrated to save money. Phosphate-free, biodegradable, and readily disposable. Low-foaming, high-wetting detergent for maximum performance. Free rinsing to give users reliable results and no interfering residues. Ideal for clean-in-place (CIP) cleaning and floor-standing lab washing machines.

Low-Foaming Liquid Acid Cleaner Low-Foaming Liquid Acid Cleaner

Low foaming acid cleaner and rinse for high performance results from your cleaning machinery. Use to pass your cleaning validation tests for lab accreditation and plant inspection approval. 

Critical Cleaning Liquid Detergent Critical Cleaning Liquid Detergent

Concentrated to save money, this detergent replaces corrosive acids and hazardous solvents. It’s phosphate-free, biodegradable, readily disposable, and is free-rinsing to give reliable results and no interfering residues.

Acid Cleaner And Detergent Acid Cleaner And Detergent

Concentrated to save money. Phosphate free, biodegradable and readily disposable. Penetrating wetting power to save time. Free rinsing to give reliable results and no interfering residues. 

Tergajet: Low-Foaming Powdered Detergent Tergajet: Low-Foaming Powdered Detergent

Concentrated to save you money. Phosphate-free, biodegradable, and readily disposable. Low foaming heavy duty detergent for high performance results. Free rinsing to give you reliable results and no interfering residues. Ideal for under-counter and floor standing lab washing machines.

Alcojet: Low-Foaming Powdered Detergent Alcojet: Low-Foaming Powdered Detergent

Concentrated to save you money. Biodegradable and readily disposable. Non-ionic, low foaming cleaner for high performance from your cleaning machinery without damaging washer parts. Free rinsing to give you reliable results and no interfering residues. Use to pass your cleaning validation tests for lab accreditation and plant inspection approval.

Low-Foaming Liquid Detergent Low-Foaming Liquid Detergent

Concentrated, biodegradable, and disposable, this low-foaming heavy-duty detergent provides high-performance results for cleaning machinery. Use it to pass your cleaning validation tests for lab accreditation and plant inspection approval.

Alconox: Powdered Precision Cleaner Alconox: Powdered Precision Cleaner

Concentrated to save you money. Biodegradable and readily disposable. Penetrating wetting power to save you time. Replaces corrosive acids and hazardous solvents. Free rinsing to give you reliable results and no interfering residues. Use to pass your cleaning validation tests for lab accreditation and plant inspection approval.

Tergazyme: Enzyme-Active Powdered Detergent Tergazyme: Enzyme-Active Powdered Detergent
Concentrated to save you money. Biodegradable and readily disposable. Replaces corrosive acids and hazardous solvents. Protease enzyme removes proteinaceous soils, tissue, blood, and body fluids. Free rinsing to give you reliable results and no interfering residues. Use to pass your cleaning validation tests for lab accreditation and plant inspection approval.
Luminox: Low-Foaming Neutral Cleaner Luminox: Low-Foaming Neutral Cleaner

Low foaming for use in mechanical and spray washers. Neutral pH for non-corrosive cleaning, safe handling, and easy waste disposal. No chelation or alkalinity waste treatment problems. Concentrated for economical use. Free rinsing to eliminate interfering residues. Biodegradable and phosphate free.

Alcotabs: Critical-Cleaning Detergent Tablets Alcotabs: Critical-Cleaning Detergent Tablets
Special slow release tablet formulation for maximum cleaning performance from your syphon pipette washers. Concentrated to save you money. Biodegradable and readily disposable. Free rinsing to give you reliable results and no interfering residues. Use to pass your cleaning validation tests for lab accreditation and plant inspection approval.
Detergent 8: Low-Foaming Ion-Free Detergent Detergent 8: Low-Foaming Ion-Free Detergent

Detergent 8 is concentrated to save you money, biodegradable, and readily disposable. Its penetrating wetting power saves you time. It’s free rinsing to give you reliable results and no interfering residues.

CONTACT INFORMATION

Alconox, Inc.

30 Glenn St., Suite 309

White Plains, NY 10603

UNITED STATES

Phone: 914-948-4040

Fax: 914-948-4088

Contact: Jeff Phillips

EDUCATIONAL ARTICLES AND RESOURCES

  • Guidance For Lab Washer Cleaning In Life Sciences
    Guidance For Lab Washer Cleaning In Life Sciences

    The principal concern for any scientist or technician working in the laboratory is that glassware, instruments, and equipment be free of interfering residues.

  • The Benefits Of Aqueous Critical Cleaning In Medical Device Manufacturing
    The Benefits Of Aqueous Critical Cleaning In Medical Device Manufacturing

    The use of aqueous cleaning in medical device manufacturing can provide numerous benefits in terms of efficacy, minimal surface contact and reduced residue potential, and easier cleaning validation.

  • Optimize Your Critical Cleaning Process And Ensure Results
    Optimize Your Critical Cleaning Process And Ensure Results

    Getting the best results from any cleaner requires proper mixing and cleaning procedures. This article includes mixing directions for aqueous cleaning detergent and methods for monitoring performance.

  • The Benefits Of Aqueous Critical Cleaning In Pharmaceutical Manufacturing
    The Benefits Of Aqueous Critical Cleaning In Pharmaceutical Manufacturing

    The use of aqueous cleaning in pharmaceutical manufacturing can provide numerous benefits in terms of efficacy, minimal surface contact, reduced residue potential, and easier cleaning validation.

  • Cleaning Validation For Medical Device Manufacturing
    Cleaning Validation For Medical Device Manufacturing

    Cleaning validation or verification is a necessary regulatory compliance step in medical device manufacturing and reprocessing. Support from the cleaner manufacturer can save time and money.

  • Pharma Manufacturers Should Get Cleaning Validation Support From Supplier
    Pharma Manufacturers Should Get Cleaning Validation Support From Supplier

    Cleaning validation is a necessary and time-consuming part of manufacturing pharmaceuticals. The validation process can be expedited and cost reduced if the cleaner supplier can provide support.

  • Alconox To Feature Critical Cleaning Products And Detergents For Biotech And Pharma Industries At Pharma Expo Conference 2016

    Alconox, Inc. is dedicated to being the leader in critical cleaning detergents. We manufacture quality detergents made in the United States and provide outstanding technical service to the scientists and engineers with precision cleaning needs.

  • Recommended Cleanroom Detergents For Medical Device Manufacturing
    Recommended Cleanroom Detergents For Medical Device Manufacturing

    For cleanroom cleaning, users should consider liquid concentrate detergents to avoid the creation of powdered clouds in the classified environment.  

  • What Does Free Rinsing Detergent Mean?
    What Does Free Rinsing Detergent Mean?

    Q. What does free rinsing detergent mean?

  • Removing Silicone Grease From Syringes
    Removing Silicone Grease From Syringes

    A faster and more efficient method to remove silicone grease from syringes is to use very hot water for cleaning and very hot water for rinsing. 

  • Removal Of Water Spots And Oil On Pharma And Lab Glassware
    Removal Of Water Spots And Oil On Pharma And Lab Glassware

    It is very important to pay attention to how glassware and equipment is loaded in to a washer so as to minimize trapping any water from cycle to cycle.

  • Cleaning Detergents For Stainless Steel Dishwashers
    Cleaning Detergents For Stainless Steel Dishwashers

    Q. What kind of cleaner options can you provide which can be safely be used in stainless steel dishwashers?

  • Residue Testing Using UV And HPLC Methods
    Residue Testing Using UV And HPLC Methods

    Q. We are interested in Alconox® detergent for cleaning during our production process. Since we produce several kinds of medicine, we need to be sure Alconox® do not leave any residue after cleaning. We want to test the residue of Alconox® by UV method or HPLC method. Could you send reference or guide on these methods?

  • Residue Testing With pH Strips
    Residue Testing With pH Strips

    Q. Can I use pH paper to confirm cleaning and rinsing of labware to comply with lab accreditation requirements?

  • Cleaning pH Probes And Dissolved Oxygen Probes
    Cleaning pH Probes And Dissolved Oxygen Probes

    Dissolved oxygen and pH probes used in fermentation vessels can get develop buildup from the fermentation media that degrades the probe performance and increases the likelihood of contamination.

  • Inorganic Residue Removal Via Clean-In-Place
    Inorganic Residue Removal Via Clean-In-Place

    As a rule of thumb, alkaline detergents are best for organic, oily residues, while acidic detergents are best for inorganic residue like salts and oxides.

  • Detecting Residues In Cleaning Validation
    Detecting Residues In Cleaning Validation

    When beginning cleaning validation, a company must identify the residues to be tested and then select the best detection method.

  • Nanotechnology Critical Cleaning For Quality & Safety
    Nanotechnology Critical Cleaning For Quality & Safety

    Nanotechnology is currently employed across a wide range of industrial, research, and academic applications. Stringent cleaning protocols are essential to the successful fabrication of nanotechnology particles, structures, and systems.

  • How To Detect Detergent Residue To Maintain Laboratory Accreditation Guidelines
    How To Detect Detergent Residue To Maintain Laboratory Accreditation Guidelines

    The following test procedures are suitable for detecting detergent residues resulting from improper rinsing and can be used to meet laboratory accreditation guidelines and questionnaires such as the College of American Pathologist program of State water lab accreditation programs.

  • The Role Of pH And Residue In Pharmaceutical Cleaning
    The Role Of pH And Residue In Pharmaceutical Cleaning

    A great deal is known about how pH affects aqueous critical cleaning. Typically, alkaline cleaners are used on oily residues and acidic cleaners are used on inorganic residues.

  • Factors To Consider When Cleaning Pharmaceutical Equipment
    Factors To Consider When Cleaning Pharmaceutical Equipment

    Typically pharmaceutical operations require transition from bench scale R&D to pilot studies to full-scale manufacturing.

  • The 7 Most Important Questions To Ask When Selecting An Aqueous Cleaner

    Today's aqueous critical-cleaning detergents are blended for specific applications. Substrate, degree of soil load, and cleaning processes are all important considerations when selecting a detergent. 

  • What You Should Know About Pharmaceutical Cleaning Validation
    What You Should Know About Pharmaceutical Cleaning Validation

    Cleaning validation is a necessary and time consuming part of manufacturing pharmaceuticals. The validation process can be expedited and cost of validation can be lowered if the cleaner supplier can provide support, allowing for pharmaceuticals to get to market faster and at a lower cost. This paper outlines the basics of cleaning validation, as well as discussing the kinds of support services you should seek from your supplier of critical cleaning products in order to optimize your cleaning validation process. By Malcolm McLaughlin

  • Minimizing Surface Residues With Aqueous Cleaning

    The benefits of employing aqueous cleaning in pharmaceutical manufacturing are numerous. Virtually any pharmaceutical manufacturing equipment from tablet press to a stainless steel mixing tank can achieve their defined critically clean criteria using aqueous cleaning. Typically aqueous cleaners are formulated to ensure maximal cleaning performance by using key ingredients such as surface active agents (surfactants) that are excellent wetting agents that allow the cleaning solution to penetrate into crevices while getting under soils to allow for removal. Often very dilute solutions of aqueous cleaner effectively removes even worst case substances off a variety of hard surfaces including stainless steel, glass, plastic, or porcelain. By Malcolm McLaughlin

  • A Guide To Labware Washer Cleaning

    The principal concern for any scientist or technician working in the laboratory is that glassware, instruments, and equipment be free of interfering residues.

  • Aqueous Critical Cleaning: Applications In Medical Device Manufacturing Aqueous cleaners are suitable for a range of cleaning methods commonly employed in medical device manufacturing including ultrasonic, manual, soak and automated. The range in formulation from acidic to basic, high emulsifying to low foaming, and availability of liquid concentrates to powder blends ensures that a cleaner can be found to clean whatever residues are encountered using whatever the cleaning method is being used. Submitted by Alconox
  • How To Choose Alkaline Or Acid Pharmaceutical Cleaners A great deal is known about how pH affects aqueous critical cleaning. The first step is for you to identify the residue that needs to be removed and then determine the optimal pH range that will remove it. By understanding the structure, functional groups, molecular polarity, solubility and molecular weight of the residue being removed, it is possible to determine if an alkaline or acidic cleaner would work best for a given cleaning method. Submitted by Alconox