ABOUT US

ILC Dover, an Ingersoll Rand business, is a global leader in engineered flexible containment solutions for the pharmaceutical and biopharmaceutical industries. With more than 25 years of expertise in single-use powder and liquid handling systems, ILC Dover enables manufacturers to safely process highly potent active pharmaceutical ingredients (HPAPIs), protect operators, and ensure product integrity across the drug development and manufacturing lifecycle from early-stage R&D through commercial production. 

Our portfolio of single-use containment technologies, including flexible isolators, closed transfer systems, and powder handling solutions, is designed to meet the evolving demands of modern pharmaceutical manufacturing. By containing processes at the source, ILC Dover solutions help reduce cross-contamination risk, minimize cleaning validation requirements, and support compliance with cGMP, FDA, and global regulatory standards. 

Serving advanced therapeutic applications such as biologics, cell and gene therapy, antibody-drug conjugates (ADCs), and GLP-1 manufacturing, ILC Dover combines deep material science expertise with innovative engineering to deliver scalable, high-performance containment systems. Our solutions are proven to improve operational efficiency, accelerate time to market, and maintain the highest standards of safety and quality in aseptic and high-potency environments. 

With global manufacturing capabilities and ISO-certified facilities, including ISO Class 7 cleanroom production environments, ILC Dover delivers regulatory-compliant, high-quality single-use systems designed for consistency, reliability, and performance at scale. 

PRODUCTS

Ensure unmatched purity across your process lines. Discover how cGMP-manufactured WFI quality water supports critical formulation, buffer prep, and cleaning workflows.

Maintain low nanogram containment thresholds during toxic linker compounding. Implement a disposable negative pressure isolation assembly with integrated double-stage exhaust filters.

Maintain a Grade-A environment for sterile fill-finish with a dual-pressure aseptic isolator. Accelerate campaign turnarounds using integrated vaporized hydrogen peroxide.

Secure big-bag transfers with solid-machined stainless steel clamping mechanisms. Ensure dust-free, airtight connections for charging and discharging bulk process materials.

Overcome powder flow and shearing challenges with a single-use fluid mixing system. Harness the Venturi effect to achieve fast, homogeneous dissolution for media and buffer preparation.

Establish safe barrier protection in minutes with a portable benchtop isolator. Secure containment for hazardous materials or inert gas processing across flexible laboratory scales.

Enhance laboratory safety with a portable, battery-operated negative pressure benchtop isolator featuring integrated HEPA filtration for immediate operator protection.

Secure your bulk powder transfer processes without sacrificing efficiency. Learn how robust, zipper-style single-use closures optimize product recovery and maintain strict containment.

Optimize material flow and contamination control in cleanroom environments. Learn how integrated containment and transport systems streamline operations and support structured 6S workflows safely.

Learn how single-use isolator technology, purpose-built for ADC manufacturing, eliminates cleaning protocols and delivers containment performance below 10ng/M³.

Handling highly potent active pharmaceutical ingredients calls for containment systems that protect operators while maintaining strict OEL thresholds below 0.1 μg/M3 throughout every transfer step.

Handling highly potent active pharmaceutical ingredients safely requires precise pressure control and automated breach response that many facilities struggle to maintain consistently.

Discover the advantage of platinum-cured silicone tubing, along with what quality tubing looks like in action and how it can streamline and secure your biomanufacturing processes.

The EZ BioPacZip is the latest evolution in the tried-and-true EZ BioPac® line. Combining upper and lower integrated assemblies that zip together to form a solid barrier, ILC Dover’s EZ BioPacZip is the ultimate solution for transferring dry powders for media and buffer preparation during drug development and manufacturing. Its fully closed-loop design eliminates the risk of cross-contamination and operator exposure while facilitating meticulous weight adjustments to meet precise target weights in a contained and controlled format.

The efficient mixing of powders into liquids is a crucial step in profitable biopharmaceutical manufacturing. For operations where low shear and high product integrity are required, no other technology performs as well as the JetMixer™ System from ILC Dover.

Have protection on your side with the only NIOSH approved Air-Purifying Escape Respirator with a powered ventilation system.

Explore a variety of PAPR hoods and headcovers along with their individual components such as filtration cartridges, power supplies, air delivery systems, and waist belts.

Review the details of three cartridges for pharmaceutical use including variations in their flow rates and percent of leakage.

Learn about a system of single-use containers and accessories designed for handling pharmaceutical intermediate and excipient powders with moderate potency.

Learn about a state-of-the-art powered air purifying respirator through images and descriptions of what is provided in each kit.

Check out the features and benefits of the E-Crimp Tool, as well as details on the parts and what the CrimpLoc Kit includes.

Learn about flexible containment solutions that are eliminating problems associated with traditional metal and glass systems for powder handling in the pharmaceutical industry.

Check out an integrated solution for materials supply and packaging options provided by an industry-leading supplier of powder containment and transfer solutions.

Explore which options meet your needs for diverse applications by learning the benefits of cGMP raw material and their standard packaging sizes.

Learn about a custom chemical bulk packaging service that offers high-purity raw materials in precise amounts in a variety of ready-to-use configurations for cGMP manufacturers.

GuardianPac is ILC Dover’s engineered flexible intermediate bulk container system for handling non-hazardous powders used in pharmaceutical processes. View the technical specifications of the GuardianPac and it's key features.

Explore Single-Use Fluid Transfer Assemblies that can streamline your development and manufacturing by providing a high-quality, rapid, and disposable sterile fluid transfer solution.

High-purity water used for the preparation of cell culture media, buffers, and aqueous reagents.

Explore Water for Injection Quality Water produced in a cGMP-compliant USA facility and meets monographs for USP, PhEur, and JP.

ILC Dover is 100% focused on containing your process to get your product to market fast, safe, and pure. Our single-use containment solutions leverage our patented and industry-leading ArmorFlex® films to deliver extreme durability for a lower cost.

Our JetBreaker powder delumping system allows for the addition of difficult to mix powders that have large clumps to keep your process moving and allow you to dissolve powder more rapidly.

The ArmorFlex® Powder Mixer offers an array of advantages over competitive systems like the Tri-blender.

The efficient mixing of media and buffer powders into liquids is a crucial step in profitable pharmaceutical and biopharmaceutical manufacturing. For operations where low shear and high product integrity are required, no other technology performs as well as the patented venturi system used by the ILC Dover ArmorFlex® Powder Mixer.

Handling today’s higher-potency active pharmaceutical ingredients (HPAPIs) presents ever-increasing regulatory concerns — especially within manufacturing-area isolators and lab areas, and for flexible GMP chambers where airflow, temperature, humidity and pressure differentials exist from room to room.

The JetVent™ system’s precise fan speed delivers accurately controlled negative air pressure to ensure proper flow into flexible-wall isolators, while reducing the risk of worker exposure.

The ILC Dover Continuous Liner is an easy-to-use system that has been proven effective in containing active pharmaceutical ingredients and other hazardous compounds.

De-agglomeration of powder blocs according to GMP standard.

The pneumatic POSITIVE pressure conveying (or PRESSURE conveying) is dedicated  to the transfer of larger quantities of powder or granulates under following conditions:

The mixer is loaded with the individual raw materials exactly according to the formulation. The combination of Dosicon®  weighing equipment with suction conveying units fulfils this task. Fundamental advanrages of JetSolutions automatic multi-component dosing are high dosing accuracy (for quantities ranging from a few hundred grams to several hundred kilos), the prevention of cross-contamination risks, and freedom from dust.

Dust-free bulk powder transfer from cardboard boxes, sacks or drums by means of a feed hopper with weighing frame. Positive raw material identification and registration by means of barcode scanners.

Thanks to its weighing terminal IT 9000 as well as its dosing device Multi-Dosimat, JetSolutions SA offers reliability and precision for filling powders or granulates into IBCs, boxes, bags, trucks, etc.

Storage of pharmaceutical compounds is a function of the storage process and not a specific containment driven requirement per se. This is the case whether you are processing in a contained fashion or performing non-contained processing into open kegs with simple drum liners.

Another proven method for cGMP processing is also available now using drums, a conical drum funnel and drum lifts.

Flexible Containment for offloading drummed materials in a safe and efficient manner is provided by the Drum Transfer System (DTS) platform.

Used for lab scale and production operations at multiple International Pharma manufacturers, our Granulator containment technology applications take the idea of retrofits to another level.

Process Area Barrier Curtains are a useful tool in improving the containment levels in existing installations and as a method to restrict access.

Our continuous liner system has been applied to production level V-Blenders. The low profile design was used in this application to support clearance limitations with this pre-installed piece of process equipment.

Tray Dryers are a common method of dryer wetcakes and granulated drug products. This is especially true in the early product development phase.

Another ILC innovation in the area of flexible containment is the design of the advanced crimping system.

Containment solutions for the contained offloading of Aurora Filters.

The DoverPac® Bag In/Bag Out (BIBO) containment system is a family of contained transfer designs for multiple processes. The primary components for this validated operation consist of multiple groove canisters, docking interface hardware, and softgoods in either continuous liner form or discreet liners.

CONTACT INFORMATION

ILC Dover, An Ingersoll Rand Business

One Moonwalker Road

Frederica, DE 19946

UNITED STATES

Phone: 1-302-335-3911 ext. 1506

Contact: ilcdover.com/en/company/locations/

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