ABOUT US

SP Scientific Products (SP), is a leading global provider of state-of-the-art fill-finish drug manufacturing solutions, laboratory equipment, research, pilot and production freeze dryers, laboratory supplies and specialty glassware. SP's products support research and production across diverse end user markets including pharmaceutical, scientific, industrial, semiconductor and healthcare. Our flagship brands Bel-Art, FTS, Genevac, Hotpack, Hull, i-Dositecno, VirTis and Wilmad-LabGlass offer best in class product solutions that make a difference in people's lives and together represent over 400 years of experience, quality and innovation. SP is headquartered in Warminster, Pennsylvania with production facilities in the USA and Europe. For more information on SP, visit www.scientificproducts.com.

SP SCIENTIFIC PRODUCTS

Fully automatic sterilization/depyrogenation tunnels for vials, syringes and ampoules for pharmaceutical manufacturing. SP PennTech is the only manufacturer of continuous processing tunnels in the United States for pharmaceutical manufacturing

The Freezemobile Large Capacity Freeze Dryer is available with condenser capacities of 25 or 35 Liters. Condenser refrigeration packages of -53, -70 and -85C are available to allow configuration for a variety of solvents. A wide array of manifolds are available including stainless steel and acrylic, tree or drum manifolds, heated or unheated shelves with bulk or stoppering.

The AdVantage Pro freeze dryer with Intellitronics Controller offers users the benefit of Ethernet communication and email options. Users can monitor their cycles from anywhere they receive email. It offers the convenience of a tray dryer in a benchtop unit.

The Freezemobile Shell Bath, a floor model shell bath available in a -75C configuration, helps to decrease manifold freeze drying time. The FSB rotates the flask on its axis thereby coating the interior surface of the flask with frozen product. 

The Benchmark Freeze Dryers are custom-built production pharmaceutical lyophilizers made to meet pilot, clinical supply and production demands. Meeting your current application demands with an eye toward future demand is what we do best.

Designed specifically for low to medium speed pharmaceutical, biotech and animal health capping applications.

Designed specifically for low to medium speed pharmaceutical, biotech and animal health vial filling and rubber stopper inserting applications. The vial range is from 2-100ml in volume and output is up to 100 vials per minute. It also features an automated, recipe-driven format changeover.

 

 

The new CharpyCool is a mechanically refrigerated bench top bath that eliminates the need for costly consumables such as liquid nitrogen or dry ice. Compact and completely self-contained, the CharpyCool offers up to 8 liters of working fluid volume enabling up to 91 Charpy impact test specimens to be accommodated at temperatures between -80°C and +30°C. A powerful variable speed magnetic stirrer and vortex breaker provide excellent temperature uniformity and stability enabling superior results. PID control enables the CharpyCool to sustain precise temperature control to within ± 0.1°C. The CharpyCool includes a digital temperature display, and an optional Charpy Rack is available which allows multiple-specimen loading and easy access to monitor your testing.

The Benchmark Freeze Dryers are custom-built production lyophilizers made to meet pilot, clinical supply and production demands. Benchmark systems are available in a wide variety of configurations and are available in economical round or space saving square tray chambers.

Hotpack glassware washers are manufactured to provide extremely accurate control and years of dependable performance. Hotpack's product line of washers meet almost any glassware washer requirement.

SP Scientific provides the unique collaboration of three well-known commercial freeze drying brands - VirTis, Hull, and FTS. This positions SP Scientific as a premier supplier of pilot and production freeze dryers / lyophilizers for any application, anywhere in the world. We invite you to contact us to see how we can help you build the best freeze dryer in the world for your needs – and in your budget.

The VirTis BenchTop Pro freeze dryers have been designed to meet the needs of the most demanding research laboratories. Each system can be configured to meet present and future needs. Condenser refrigeration packages of -55°C, -75°C, -85°C and -105°C can meet the demands of both aqueous or aqueous-solvent based formulations.

The Multi-Cool low temperature bath is mechanically refrigerated with temperatures to -80C.
The FTS Systems Flexi-Cool Low Temperature Immersion Cooler is available in temperature ranges of -55C and -100C.
Hull supplies patented, highly efficient, totally automated vial loading and unloading systems to facilitate the lyophilization of parenteral, cytotoxic, and other freeze dried products with special handling requirements.
Hull designs, manufactures, installs, and services cGMP vacuum freeze drying equipment for the reliable lyophilization of a wide range of pharmaceutical and biotech products.

Designed for ease of scale-up, these models are unmatched for capabilities and performance. Designed for pilot and light production scale lyophilization, for both bulk and vial processing, these units come with an extensive list of options.

FTS Vapor traps are mechanically refrigerated cold traps that protect expensive vacuum pumps from harmful vapors which can shorten their life. The harmful vapors constitute any condensable gases such as water vapor, which, when allowed into the vacuum pump oil, cause it to break down. This results in decreased lubrication and can eventually cause failure of the pump.
The Hull Rotary Disk valve is available as a drop-in replacement for all standard butterfly valves in 20-inch, 24-inch, 30-inch, and 36-inch sizes.
Hull combines people, technology, facilities, and experience to provide customized modular systems. Our facility shop can fabricate finished vessels as well as skid mounted subassembled piping systems to be field erected.
Hull has supplied patented, highly efficient, totally automated vial handling systems for sterile product freeze-drying.
The VirTis 96 well Freeze Drying System consists of glass or plastic vials in an aluminum block specifically designed for freeze drying samples. This unique combination eliminates problems such as edge effect typically seen in standard 96 well plastic plates.

The Standard (EZ-2) is suitable for water and volatile solvents, while the Plus (EZ-2plus) is recommended for solvents with boiling points upto 165°C.

The miVac Duo Pump is suitable for use with a volatile organic solvents through to water, where as the miVac Quattro Pump is also suitable for use with some higher boiling point solvents. Both pumps have high flow rates to ensure the fastest possible concentration rate.

The miVac Duo is suitable for use with a wide range of solvents, from volatile organic solvents through to water for low sample numbers.

Bio-Cool Controlled-Rate Freezers feature temperatures to -40ºC or -80ºC, eliminate the use, handling, and storage of expendable high-pressure refrigerants (LN2), and Enable in-house cryopreservation capabilities to save time and money.

When a product is frozen in a thin layer on the inner wall surface of a large-diameter flask using a shell freezer, the overall sublimation rate significantly increases as compared to the product frozen as a plug in the bottom of a similar flask...
Rugged, stainless steel Multi-Tainers are used for freeze-drying bulky materials or products which have already been frozen in Petri dishes, serum vials, or similar containers...

ThermoJet is a precision-controlled temperature forcing system that delivers an airstream of up to 20 SCFM to rapidly change the temperature of a product or Device Under Test (DUT)...

Precise temperature control, Temperatures from -80°C to +100°C, ± 0.1°C temperature stability, Choice of two delivery line lengths...

AirJet XE from FTS Systems delivers full mil-spec temperature range (­-75C to +225C) in a compact benchtop platform and runs on standard 120 volt power

Shell freezing is the classic method for preparing samples for freeze drying.
Virtis General Purpose Freeze Dryers are ideal for a variety of freeze drying applications and are available in a range of sizes.
Freeze Drying of bridal bouquets, sympathy flowers and other floral arrangements for special occasions is a growing business for many people that want...
VirTis keeps coming up with ways to simplify research freeze-drying.
VirTis Research Freeze Dryer is custom built to meet your specific needs. From the recognized world leader in freeze dryer technology, you can expect the best.
The American Society of Mechanical Engineers' Code for pressure vessel design and fabrication is recognized throughout the world for its high standards of quality and safety...
The Hull Company combines people, technology, facilities, and experience to provide customized modular systems. Our ASME code shop can fabricate finished vessels as well as skid mounted subassembled piping systems to be field erected...
Hull has supplied patented, highly efficient, totally automated vial handling systems for sterile product freeze drying...
Remanufacturing can greatly extend the operating life of your equipment. As an original equipment manufacturer, Hull has the necessary in-house resources to re-engineer, upgrade and remanufacture freeze dryers, freezers, sterilizers, and vacuum and pressure vessels...
Freeze Dryer - Designed for ease of scale-up, Hy-Pro and Lyo-Pro freeze dryer models are unmatched for capabilities and performance...
Freeze Dryer - The Benchmark Series Freeze Dryer is engineered to process pilot to production scale batches of pharmaceutical and biotech products. Benchmark series freeze dryers have numerous options that allow the customer to configure the freeze dryer to fit any pharmaceutical application...
Superior corrosion resistance in a vacuum vapor trap. The Titan® Trap from FTS Systems is the first cold trap to incorporate a titanium helical coil design and Teflon coated stainless steel chamber, to provide maximum efficiency for vacuum trapping of corrosive vapors to -100C.

Chillers - Dependable cooling for laboratory applications...

Increase your ROI and decrease cycle optimization time with SMART Freeze-Dryer technology. SMART helps eliminates the trial-and-error approach normally involved in developing new lyophilization cycles allowing researchers more time to work on formulation strategies.
A pilot scale freeze dryer designed for fast drying and high condenser loading applications. New high capacity internal coil condenser is configured to add the enhancements and features of an external condenser

The miVac DNA is an ideal small concentrator for the molecular biology laboratory. This centrifugal concentrator is capable of removing low volumes of water and organic solvents from a variety of sample formats including tubes, microplates, vials, and round bottom flasks.

Developed largely as a consequence of users’ demands, the Rocket Evaporator is designed to dry or concentrate as many as six flasks, each containing up to 450mL of solvent.

Building on the proven success of the Wizard Control System, Wizard 2.0 again exceeds the control power and user-friendliness of any other embedded microprocessor control system. With complete recipe management and full alarming, it provides full process automation for the VirTis freeze dryer line, including AdVantage, Genesis, and Ultra Lyophilizers.
Genesis Series Freeze Dryers are the most versatile freeze dryers for pilot, research, or small scale production applications. VirTis has been manufacturing, installing and servicing Genesis freeze dryers for over 25 years...

Virtis has managed to pack valuable features in this small freeze dryer system for your laboratory needs. The smallest shelf freeze dryer offered, this equipment can be configured with a manual or automated control system and as a bulk or stoppering freeze dryer.

Chillers - Midsize recirculators / chillers for maximum cooling...
Chillers - The widest, precision-controlled temperature range available...

Chillers - Ultra-low temperature recirculators provide maximum heat removal to -90°C...

Filters- Acid filters protect vacuum pumps when freeze drying acidic or organic solvents...
Pilot to production scale freeze dryers - The Benchmark Series Freeze Dryers are engineered to process pilot to production scale batches of pharmaceutical and biotech products. Custom configured to your freeze drying requirements.
Hull designs, manufactures, installs, and services cGMP vacuum freeze drying equipment (lyophilizers) for the reliable preservation of a wide range of pharmaceutical and fine chemical products.
Hotpack Under Counter Glassware Washers are engineered for durable, reliable and energy efficient operation. For laboratories with space restraints pick the Space Saver Double Stack Glassware Washer and put two Under Counter Glassware Washers together in a single vertical tower.
Production Freeze Dryer - Freeze dryers, or lyophilizer, are used for the reliable preservation of a wide variety of heat sensitive products and demands the highest standards of reliability and control...
The Virtis Ultra Series Freeze Dryer has been re-engineered to handle all of your applications from phase one research through production clinical trial batches...
Mechanically Refrigerated Bath by SP Industries, Inc.

SP Equipment Service has an expertly staffed Global Service Center to answer your questions regarding your FTS, VirTis,Genevac or Hotpack equipment. We can also arrange to have one of our factory trained service technicians come and service any of your equipment

As the Service and Support arm for the SP Scientific Equipment Manufacturing Divisions, SP TechCare is uniquely qualified to provide for all your validation needs.

STERILE FILLING OFFERINGS

Filling and closing machine, specially designed for vials and, syringes and cartridges in nest.

In i-Dositecno we design, build and sell filling systems for the pharmaceutical and cosmetic industries. From our beginnings 15 years ago, i-Dositecno has developed a complete range of machinery, giving to the pharmaceutical market, our way of work, with fully servomotorized machine, in order to facilitate the format changes and optimize the production. We are now present in many of the pharmaceutical industries, with a lot of references.

GENEVAC PRODUCTS

Developed largely as a consequence of users’ demands, the Rocket Evaporator is designed to dry or concentrate as many as six flasks, each containing up to 450mL of solvent.

The Standard (EZ-2) is suitable for water and volatile solvents, while the Plus (EZ-2plus) is recommended for solvents with boiling points upto 165°C.

For laboratories looking to concentrate larger numbers of biological samples presented in a range of different formats the miVac Quattro from Genevac is the perfect high capacity sample concentrator.

The miVac DNA is an ideal small concentrator for the molecular biology laboratory. This centrifugal concentrator is capable of removing low volumes of water and organic solvents from a variety of sample formats including tubes, microplates, vials, and round bottom flasks.

Genevac HT series evaporators are the ideal solution for parallel evaporation bottlenecks in high throughput and production laboratories having high performance and high sample capacities.

The Rocket Evaporator uses patented vacuum technology to evaporate solutions to dryness, or a concentrate, rapidly and safely.

PENNTECH PRODUCTS

PennTech's model FS-22 is a machine designed specifically for low- to medium-speed pharmaceutical, biotech and animal health filling and rubber stopper inserting applications.

The EVW-Series is the industries’ only in-line decontamination system to completely encapsulate vial caps with a watertight seal. This allows for increased washing pressures for thorough cleaning; the entire vial body including the bottom is exposed to the water jets.

PennTechs customized Automatic Loading/Unloading Systems can be installed as part of a new freeze dryer installation and as retrofit with almost all existing freeze dryers.

The RW-1150 is a high speed  automatic vial washer for pharmaceutical and biotech applications with an output of up to 400 vials/min (2ml). Vial range 2-500ml. (change parts requires). Standard features include:  Recycling of WFI, intermittent spraying and automatic lid lift mechanism.

PennTech offers a state-of-the-art aseptic capping machine, model AC-6. The machine is designed specifically for low to medium speed pharmaceutical, biotech and animal health capping applications.

The FSC-1R is an intermittent-motion filling, stopper inserting, capping machine designed for aseptic applications in a class-100 environment. The machine is designed for vials from 2 ml to 100 ml with an output of 20-30 vials per minute.

A uniquely simple, yet effective, method of loading pharmaceutical vials into the depyrogenation tunnel. 

The TP-1 is compact tunnel loader suitable for sterilizing tunnels with a belt width of up to 600mm. The TP-1 accommodates the full range of pharmaceutical vials, from 2-100ml, without change parts. Even small unstable 2ml vials are gently loaded onto the tunnel belt without tipping over. The TP-1 allows full access to the tunnel infeed area.

The TL-100 is controlled by a Programmable Logic Controller (PLC) and will handle plastic and glass vials with speeds of up to 200 vials per minute (depending on vial diameter and tray size). It is designed to handle trays up to 610 mm (24") wide (open end) and up to 610 mm (24") deep. Tray materials can be metal, cardboard, corrugated plastic, or rigid plastic.

The TL-200 has two loading platforms (the TL-100 has one), so that two trays are loaded simultaneously. Once the trays are full, the operator replaces one of the loaded trays with an empty one and the machine immediately resumes loading that tray. The operator then replaces the other loaded tray with an empty one. When in place, the machine will resume loading both trays. The process is seamless; there is no additional work to be done or buttons to be depressed by the operator. Once a tray is full, the loading process stops and a yellow light and audible signal indicate that the tray can be replaced.

The AC-6 is a 6-head heavy duty in-line rotary capping machine, GMP Design: all stainless steel construction, with tempered glass doors and windows. 

The RW-500 is the industries smallest automatic vial washer and is designed for low output  pharmaceutical and biotech applications. The output is 40-100 vials/min, dependent on the vial format. Typical batch size: 10,000-25,000 vials. Vial range 2-100 ml (change parts required). Rotary infeed table with automatic loading of the vials into the vial holders. Options include:  Recycling of WFI, intermittent spraying and automatic lid lift mechanism. Changeover time: 20min.

The RW-800 is a medium-speed automatic vial washer for pharmaceutical and biotech applications with an output of up to 200 vials/minute (2 ml). The RW-800 is a compact machine with a footprint of 90 cm x 130 cm (36” x 51”) and a vial range of 2 to 250 ml.

PennTech manufactures an array of standard and custom sanitary conveyors and accumulation tables, including transfer disks. All systems are of the highest quality, completely customizable and direct driven (zero maintenance).

The TP-4 row-by-row tunnel loader is designed for tunnels with belts over 600mm wide.  The benefit of the TP-4 is that the tunnel belt movement can be synchronized with the TP-4 movement at vial format level. This results in an optimum tunnel loading pattern without gaps in the vial pack. This in turn contributes to an even heat distribution in the sterilizing chamber of the tunnel. The TP-4 is PLC-controlled so that the loading speed and travel distance are automatically set per vial format.

Washing vials by hand is quickly becoming a thing of the past. With cGMP issues increasing in Pharma, PennTech has designed and manufactured the perfect aseptic solution to help keep Compounding Pharmacies USP and cGMP Compliant.

CONTACT INFORMATION

SP Scientific Products

935 Mearns Road

Warminster, PA 18974

UNITED STATES

Phone: (215) 672-7800

Contact: Sales Department

FEATURED ARTICLES

  • Accelerated Probe And Primer Production To Enable COVID-19 Testing With The SP Genevac HT Series 3i Evaporator

    As the novel coronavirus (COVID-19) pandemic is progressing throughout 2020, it has become evident that millions of testing kits are needed internationally every single day. This article explores how a leading provider of tools and technologies for genetic analysis, LGC, Biosearch Technologies, is aiding in the fulfilment of this demand, assisted by evaporation technology from SP Genevac.

  • Using Parallel Evaporators To Escalate COVID-19 Test Kit Preparation

    An issue for all countries now is how to obtain a sufficient supply of COVID-19 testing kits, when the international demand for them has never been higher. As laboratories around the world scale up their production of PCR test kits to aid the global fight against the virus, improvements to the workflow for producing testing kits are urgently needed to increase the efficiency of test kit production. Centrifugal evaporators offer an ideal solution to improving the efficiency of test kit production.

  • Drug Discovery Workflow For PROTAC With A Focus On Eliminating Bottlenecks In Evaporation

    An emerging modality of therapeutics called PROteolysis TArgeting Chimeras (PROTACs) could enable the design of new drugs targeting “undruggable” proteins, which make up to 85% of the proteome. This article introduces PROTACs and the benefits they can offer to the drug discovery field, before discussing how the issues with their synthesis can be overcome.

  • Putting Fill-Finish Customization Into Your Line Of Sight

    There is a growing need for a complete package of rapid product development tools and scalable, good manufacturing (GMP) compliant, aseptic fill-finish production lines optimized for small batch applications. This article discusses the development and manufacturing challenges, and highlights the key considerations required when evaluating product development tools, selecting equipment, and optimizing small batch fill-finish lines.

  • ControLyo - What Can It Do For Your Business?

    SP takes you on a visual case for increased profitability, batch homogeneity, and shorter run times during commercial lyophilization using controlled nucleation. Here, you will see how controlled nucleation can make your scale up seamless.

  • SP Hull Versa-Line Fill-Finish Solutions

    The SP modular Versa-Line fill-finish system and Line of Sight™ freeze dryer tools, technologies and equipment provide product development and configurable full line solutions.

  • The Importance Of Defining A Practical Performance Test For Vial Washers

    There are several methods for validating the cleaning effectiveness of washers, but all include some sort of contamination and then an evaluation of the effectiveness of the removal of the contamination. Different pharmaceutical companies have different preferences in test methods but it is important to define the expected results so they are achievable and evaluate the cleaning effectiveness of the important parts of the vial. This paper explains the pros and cons of different washer systems.

  • Minimizing Aseptic Pharmaceutical Manufacturing Risks With The Inclusion Of Depyrogenation Tunnels

    Depyrogenation, as the name implies, is the process to remove pyrogens, including bacterial endotoxins from vial surfaces. The two most common methods for depyrogenation are batch ovens and depyrogenation tunnels, but there are different risk levels associated with these two processes. This paper discusses these risks and the opportunities for mitigation.

  • Factors That Influence Product Resistance And Methods To Measure Product Resistance

    Product resistance (Rp) is the resistance to vapor flow through the dried layer out of the vial during primary drying. Along with the vial heat transfer coefficient (Kv), product resistance is a key determinant of the product temperature. It can provide instantaneous structural information about cake morphology at the point of measurement. However, characterizing Rp remains the weakest part of any predictive model of primary drying. This article summarizes a recent webinar that discussed the factors that influence product resistance and ways to measure it during primary drying of the lyophilization cycle for products in vials.

  • Freeze-Drying COVID-19 Diagnostics: Formulation & Process Development And Lyophilizer Selection

    Lyophilization may be considered a relatively gentle drying process, but there are still risks and pitfalls when applying it to biomolecular reagents in diagnostic tests that are different to the freeze-drying of general pharmaceuticals. Reagents typically used in ELISA and PCR based diagnostic kits for diseases, such as COVID-19 tend to contain labile  components, such as enzymes that need preserving for longevity in the supply chain or antibodies to test for a patients response to the virus, which can be challenging to stabilize for commercial use. This article summarizes a recent webinar exploring various aspects of formulation and cycle development in the lyophilization of diagnostic reagents, including those required for COVID-19 testing that may be different to regular diagnostics.

VIDEOS