Powder Technology for Pharmaceutical Development and Manufacturing
September 26 - 28, 2018 - London UKPharmaCourses Ltd
info@pharma-training-courses.com
Phone:2081332605
Powder properties have a major impact on formulation, development and manufacturing of Oral Solid Dosage forms. They also play an important role in meeting the requirements of Quality by Design for OSDs. In this course we examine powder properties and their role in these important processes, so that attendees can understand * The influence of drug substance properties on formulation development how and why particular tablet components are selected and what impact they have on powder properties and tablet behaviour * Manufacturing method selection and the importance of powder flow * Mechanisms of powder mixing and segregation * Powder properties, Critical Quality and Material Attributes, and the Product Control Strategy * Effects of blending behaviour and scale on Critical Process Parameters * The relationship between input material properties and tablet properties Proper integration of these elements is essential to achieve “Quality by Design” because data from each phase is used to control the next step in the development process. By achieving proper integration based on sound scientific principles based on powder technology, many development and production problems can be avoided, and formulation robustness can be improved. The course includes case studies of tablet formulation development and a detailed step by step analysis of all elements of the tablet manufacturing process. By the end of the course the attendees will be able to recognise key powder properties which affect process performance, and make improved judgements about how to improve processes.