Gene Therapy Immunogenicity

August 4 - 6, 2020 - MA US

Hanson Wade
Phone:+44 020 3141 8700

Immunogenicity compromises both the efficacy and safety of gene therapies and thus represents one of the most prominent challenges that must be overcome in the field. Uniting translational, clinical, regulatory and manufacturing gene therapy functions, the inaugural Gene Therapy Immunogenicity Summit is the industry’s definitive meeting enabling you to better measure, modulate and predict immune response and drive transformative treatments through the clinic to patients more quickly and efficiently.Key topics of discussion include:Evaluating the suitability and success of current immunosuppression agents in the context of gene therapyEmploying risk assessment tools to develop clinical bioanalytical and immunogenicity monitoring strategiesDissecting the immunogenicity of gene therapy vectors to better understand immunology safety concernsBetter understanding the innate immune response and its implications for gene therapy transductionEvaluating the resolution and throughput of technologies to define empty vs full capsid presenceImplementing the use of preclinical risk assessment tools to drive clinical immunogenicity strategies for gene therapy modalitiesWhat the implications are for the safety and efficacy of gene therapies if re-dosing is to occur

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