Cleanroom Whitepapers and Case Studies

1. How To Take Your Process To A Closed System 4/22/2025

   Understand the critical considerations for implementing closed systems in bioproduction, from vessel selection to workflow customization for optimal efficiency and safety.

2. SRP-Funded Technology Provides Affordable PFAS Testing For Homeowners 7/6/2026

   Widespread chemical contamination leaves many small water systems without viable testing options.Discover how an innovative, plant-based extraction method delivers affordable, highly accurate screening to identify complex contaminants and protect public health.

3. Adapting To USP 382: Enhanced Testing Protocols For Parenteral Packaging Systems 7/25/2025

   USP 382 introduces system-level, function-specific testing for elastomeric components in parenteral packaging, improving container integrity, sterility, and patient safety through enhanced protocols.

4. Leak Detection Program For Roswell, New Mexico 3/2/2026

   Harnessing satellite intelligence allows utilities to pinpoint hidden underground leaks with precision. By focusing field crews on high-probability clusters, municipalities can drastically reduce water loss, optimize repair budgets, and prioritize critical infrastructure replacement projects.

5. GeoTree - Delaware DOT Large Diameter Metal Plate Arch Rehabilitation With GeoSpray Geopolymer Mortar 4/6/2026

   Trenchless geopolymer technology provides a high-strength, structural solution for failing large-diameter arch culverts.This approach eliminates the need for costly bridge replacements, offering a 70-plus-year service life with minimal environmental impact and significantly faster project timelines.

6. Nucleic Acid-LNP Ultrafiltration And Diafiltration 5/5/2026

   Downstream filtration can make or break LNPs at scale. See how membrane format, loading, and shear affect recovery and stability — and how alternative TFF lowers scale‑up risk.

7. Hot Springs Combats Aging Infrastructure Challenges With Xylem Digital Solutions 4/30/2025

   The City of Hot Springs, Arkansas knows the challenges of dealing with aging infrastructure well. The city’s 143-year-old system covers 923 miles of water mains in rocky terrain, making it difficult to detect leaks. That is why the utility’s water department decided to act. 

8. The Impact Of Annex 1 (2022) On Sterility Assurance 4/24/2025

   Airflow visualization studies, crucial for GMP compliance, validate unidirectional airflow effectiveness in contamination control. Discover their enhanced role in quality by design and revised Annex 1 guidelines.

9. How Honolulu Board Of Water Supply Uses Satellite-Based Leak Detection 3/5/2026

   Satellite-based radar technology allows water utilities to identify non-surfacing leaks that traditional methods often miss. By pinpointing underground moisture signatures, municipalities can significantly reduce non-revenue water and meet conservation goals through more efficient, data-driven field inspections.

10. Manufacturing Of Cytotoxic And Non-Cytotoxic Drugs In A Multiproduct Facility 10/16/2024

    The experience and expertise of the CMO is crucial to avoid the risk of cross-contamination of the drug product, as failures or weaknesses in this process can pose risk to the end-user.