Cleanroom Whitepapers and Case Studies

1. Tablet Manufacturing Technologies For Solid Drug Formulation 4/2/2025

   Compressed tablets are common oral solid dosages that contain the API and various excipients. Learn about the critical steps in selecting manufacturing methods and excipients to achieve the desired therapeutic effects and stability.

2. Understanding Viral Clearance During Anion-Exchange Chromatography 3/26/2024

   A design of experiments (DoE) study examined the anion-exchange process in general and to draw possible correlations between such properties and overall viral clearance capability.

3. How To Avoid Sticking And Picking In The Tableting Industry 9/23/2024

   Review strategies to mitigate sticking and picking risks in the tablet industry, and learn how you can foster improved tablet production processes, ensuring higher quality and consistency.

4. Buffers And Process Liquids For Biopharmaceutical Production: Considerations For Scale-Up And Outsourcing 5/7/2024

   For small and midsize biopharmaceutical organizations, outsourcing buffer and process liquid preparation, quality testing, and storage could significantly streamline operations and reduce regulatory risk.

5. Hot Springs Combats Aging Infrastructure Challenges With Xylem Digital Solutions 4/30/2025

   The City of Hot Springs, Arkansas knows the challenges of dealing with aging infrastructure well. The city’s 143-year-old system covers 923 miles of water mains in rocky terrain, making it difficult to detect leaks. That is why the utility’s water department decided to act. 

6. Digital Standardization: Accelerating Gene Therapy Tech Transfer With Confidence And Compliance 4/1/2026

   Fragmented, manual data practices slow tech transfer and increase risk; centralized digital CMC systems standardize workflows, improve transparency, and accelerate onboarding while maintaining compliance.

7. How Omaha Reduced Water Loss And Costs With Smart Hydrant Monitoring 3/5/2026

   Permanent acoustic sensors turn fire hydrants into a high-tech defense against water loss. By monitoring pipe sounds 24/7, utilities can identify and fix hidden leaks before they cause expensive, unplanned service disruptions or emergency flooding.

8. NWG's MDM Promotes Sustainability 4/16/2025

   Northumbrian Water Group (NWG) serves over 4.5 million customers across Northumberland, Essex, and Suffolk County in the UK, prioritizing both customer satisfaction and environmental stewardship. To enhance its water management capabilities, NWG has partnered with Siemens to implement an advanced meter data management (MDM) solution.

9. Leveraging Single-Use Solutions To Solve Working Cell Bank Challenges 8/28/2025

   Discover how custom manifolds enhance allogeneic therapy development from formulation to commercialization by improving process control, scalability, and efficiency.

10. Contamination Control Of Particulate And Shuttle Blow-Fill-Seal Compliance 2/24/2026

    Does shuttle blow-fill-seal truly meet Annex 1’s stricter contamination standards? New particle burden data challenges industry assumptions and reveals what manufacturers need to know.