Featured Articles

  1. Advancing Cell Therapies With Lipid Nanoparticles 3/24/2025

    Cell therapies, using reprogrammed immune cells, offer innovative treatments for diseases. Discover how lipid nanoparticles (LNPs) enhance these therapies by delivering RNA for gene modulation and next-gen treatments.

  2. Replicate Bioscience And Cytiva Collaborate To Deliver srRNA-LNP Vaccines 3/24/2025

    Discover how self-replicating RNA (srRNA) can revolutionize vaccine development with sustained protein expression, lower doses, and fewer side effects to advance next-gen RNA therapeutics.

  3. Outsourcing RNA-LNP Production: A Key To Competitive Success 3/6/2025

    Manufacturing RNA-containing LNPs demands specialized expertise. Explore some of the challenges of RNA-LNP drug manufacturing and the advantages of outsourcing RNA-LNP formulations.

  4. Scaling Up An Upstream Process For Gene Therapies 2/27/2025

    It's important to evaluate your starting point when scaling an upstream process. Review key considerations for deciding between adherent and suspension cells to optimize your gene therapy process.

  5. Tackling Encapsidated Host Cell DNA To Improve Quality 2/19/2025

    Discover a cell line that enhances rAAV production by reducing host cell DNA encapsidation, improving safety and efficiency through genetic modifications that inhibit apoptotic DNA fragmentation.

  6. Toward A Gene Therapy Platform: What's The Best Format Of TFF? 1/13/2025

    Evaluate tangential flow filtration (TFF) formats and membrane chemistries for AAV gene therapy processing, assessing performance, scalability, economy, and closed processing options.

  7. Solvent-Free Purification Of D84-mer Oligonucleotide Using Capto™ PlasmidSelect Resin 1/13/2025

    Discover a solvent-free process using Capto PlasmidSelect and Capto Q ImpRes resins. They enable high-purity, scalable purification of long oligonucleotides, achieving more than 95% of full-length product purity.

  8. Single-Step Purification Of A 21-mer Oligonucleotide Using Capto™ Q ImpRes Resin 1/13/2025

    Explore how the oligonucleotide therapeutics market is advancing with scalable solutions for high-purity purification, supporting global production of life-changing RNA therapies.

  9. The Crucial Role Of Downstream Processing In Optimizing RNA-LNP Drug Development 8/28/2024

    Explore the key aspects of lipid nanoparticle (LNP) development, including the essential downstream processes of Tangential Flow Filtration (TFF) and normal flow filtration.

  10. End-To-End Manufacturing Of Autologous CAR T Cell Therapies 6/13/2024

    Learn about a modular, functionally closed, end-to-end solution for the manufacture of autologous CAR T cell therapies.