Gain a deeper understanding of the requirements, guidelines, and best practices for Annex 1 compliance whether you're in pharmaceuticals, healthcare, or any field utilizing biological indicators.
Learn about liquid submersible biological indicators (LSBI), including the three basic LSBI formats, and how caramelization due to long sterilization cycles affects the media's ability to promote spore growth.
How can your organization use this critical tool when developing your sterilization process for heat-sensitive products and low F0 cycles?
Follow our discussion on non-heat sensitive aqueous liquid product sterilization and the use of the Overkill method and Bioburden/BI method.
Learn what questions to ask when developing a sterilization method and the critical tool that can help guide your decisions.
Here, we review the information concerning biological indicators in European Pharmacopoeia General Chapter 5.1.2, which is more detailed and covers a wider scope than the previous version.
We review what to do should you ever find yourself in the situation where the probes indicate conditions that would render killed BIs, yet the units are testing positive.
We highlight vapor hydrogen peroxide (VH2O2) biological indicators (BIs) including necessary physical characteristics of the BI unit, BI types, proper BI placement, and challenges encountered.
This field guide uses current published resources to provide clarity and direction regarding best practices for validating decontamination processes using VH2O2.
We discuss the three general BI types used for monitoring the VH2O2 cycles and directions on their proper placement in the isolator.
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