Oligo Featured Content

1. Characterizing mRNA Using Ion-Pairing Reversed-Phase LC/MS 7/30/2026

   mRNA poly(A) tail analysis depends on targeted digestion, clean LC/MS conditions, and reliable deconvolution. See how RNase 4 digestion and optimized ion-pairing methods support reproducible results.

2. Pushing The Boundaries Of Chromatographic Separation 7/29/2026

   Metal-sensitive analytes often suffer from poor recovery and distorted peak shapes. Learn how inert hardware improves sensitivity and chromatographic performance for challenging analyses.

3. Comprehensive Characterization Of Oligonucleotides And Related Impurities 7/29/2026

   A two-dimensional LC/MS strategy improves the separation of coeluting oligonucleotide impurities. High-resolution sampling and automation enable deeper characterization of low-level variants.