Solid Dose Featured Articles

1. All You Need To Know About Contamination Control Strategies, Part 1 5/12/2023

   In the first of this two-part series, microbiology and contamination control specialists Vanessa Figueroa, Rebecca Brewer, and Greg Gibb, Ph.D., discuss best practices in developing contamination control strategies through the lens of the newly formalized provisions in the EU GMP Annex I, Manufacture of Sterile Medicinal Products.

2. 5 Misconceptions About Data Integrity In Pharmaceutical And Device Development & Operations 9/15/2021

   Data integrity (DI) issues in pharma and medical devices have always been there, but in my experience as a consultant, these issues have increased in frequency more recently, thus moving them to the forefront. In this article, I explain five misconceptions about data integrity in our industry.

3. How To Utilize Zeta Potential To Stabilize Pharmaceutical Suspensions 10/17/2017

   As an indicator of the suspension quality of various pharmaceutical products, using the measurement of zeta potential to yield the best products is of primary importance during product development.

4. Contract Manufacturing In China 12/4/2012

   The outsourcing of pharmaceutical manufacturing is growing most rapidly in Asia. Recently, PriceWaterhouseCoopers named China as the most attractive Asian country for outsourcing. At present, more than 100 drug manufacturing sites in China are manufacturing API or finished products for approved branded and generic drugs. By Oliver Mueller & Clifford Mintz, PhD

5. The Benefits Of Contract Manufacturing 10/25/2012

   Contract manufacturing organizations (CMOs) offer a wide array of manufacturing services to the pharmaceutical and biotechnology industries. These services can range from production of small quantities of materials for R&D purposes, larger amounts for clinical study usage and ultimately full-scale production for commercial purposes. The global contract manufacturing market primarily includes solid and liquid dosage forms and injectables.

6. Accelerated Drug Development: The Promise Is In The Process 3/21/2012

   In 1993, the FDA issued the call to the pharmaceutical industry to streamline the drug development process from discovery to First In Man. By Jan-Olav Henck, Ph.D., Chief Scientific Officer, Aptuit LLC

7. Pharma Beyond Borders: India As An Outsourcing Destination 2/1/2012
   The only thing that is constant in life (and that goes for the global pharma industry too!) is change. The need to access emerging markets with new and cost effective drugs, the diminishing blockbuster product model, and the far more complicated life cycle management programs are just some of the new and ever changing challenges that innovator pharmaceutical companies face in today’s environment. By Manoj Mehrotra
8. Preparation Of MUPS (Multiple Unit Particles System) Tablet Using Celphere™ And Preliminary Blend Of Microcrystalline Cellulose And Pregelatinized Starch 12/2/2011

   Multiple dosage forms (Pellets, Capsule, MUPS tablet etc.) show better reproducibility of the drug absorption in the body than single dosage form (Matrix tablet).

9. Direct Compression Of Very High Dose Drug Tablets Using Extremely Compactible MCC, Ceolus™ KG-1000 12/1/2011
   There are some very high dose tablets in which the drug content is near 1000mg, such as anti-HIV drugs and multi-vitamin supplements. The size of such tablets is often so large that elderly people or small children can’t easily swallow them.
10. Insights On Solid-Dose Manufacturing Roundtable 11/30/2011
    Highlights of this roundtable discussion with Regan include: solid-dose manufacturing evolution during the past 10 years, what the future holds for solid-dose manufacturing, common misconceptions with solid-dose manufacturing, and advice for those looking to purchase solid-dose manufacturing equipment. By Life Science Leader magazine