Solid Dose Featured Articles

1. How Can You Achieve Economic Compaction Of Your Raw Materials?
   12/19/2017

   In tablet manufacturing, the traditional use of a batch-based wet granulation process presents several issues. An alternative to this is dry granulation by roller compaction. However, to appreciate how roller compaction can benefit manufacturing capacity and efficiency, it is important to first understand the functionality and capability of this technology.

2. How To Utilize Zeta Potential To Stabilize Pharmaceutical Suspensions
   10/17/2017

   As an indicator of the suspension quality of various pharmaceutical products, using the measurement of zeta potential to yield the best products is of primary importance during product development.

3. Outsourcing Solid Dose Manufacturing Trends In 2014
   3/3/2014

   In 2014, the contract manufacturing market for solid dosage forms is anticipated to be $19.6B, representing 58% of the total CMO market value of $33.7B. While the market value percentage for solid dose has been drifting downward — likely related to the shift towards biologics, which are more expensive to develop and manufacture — the propensity to outsource oral solid dosage forms continues to grow modestly.

4. Contract Manufacturing In China
   12/4/2012

   The outsourcing of pharmaceutical manufacturing is growing most rapidly in Asia. Recently, PriceWaterhouseCoopers named China as the most attractive Asian country for outsourcing. At present, more than 100 drug manufacturing sites in China are manufacturing API or finished products for approved branded and generic drugs. By Oliver Mueller & Clifford Mintz, PhD

5. The Benefits Of Contract Manufacturing
   10/25/2012

   Contract manufacturing organizations (CMOs) offer a wide array of manufacturing services to the pharmaceutical and biotechnology industries. These services can range from production of small quantities of materials for R&D purposes, larger amounts for clinical study usage and ultimately full-scale production for commercial purposes. The global contract manufacturing market primarily includes solid and liquid dosage forms and injectables.

6. Accelerated Drug Development: The Promise Is In The Process
   3/21/2012

   In 1993, the FDA issued the call to the pharmaceutical industry to streamline the drug development process from discovery to First In Man. By Jan-Olav Henck, Ph.D., Chief Scientific Officer, Aptuit LLC

7. Saudi Arabia Emerges As Pharma Manufacturing Hot Spot
   2/12/2012

   The World Bank/International Financial Corporation’s Doing Business report ranked the Kingdom of Saudi Arabia 12th in the world out of 183 economies for ease of doing business in 2011 — up from 67th in 2005. By Sara Gambrill, Life Science Leader magazine

8. Pharma Beyond Borders: India As An Outsourcing Destination
   2/1/2012
   The only thing that is constant in life (and that goes for the global pharma industry too!) is change. The need to access emerging markets with new and cost effective drugs, the diminishing blockbuster product model, and the far more complicated life cycle management programs are just some of the new and ever changing challenges that innovator pharmaceutical companies face in today’s environment. By Manoj Mehrotra
9. Preparation Of MUPS (Multiple Unit Particles System) Tablet Using Celphere™ And Preliminary Blend Of Microcrystalline Cellulose And Pregelatinized Starch
   12/2/2011

   Multiple dosage forms (Pellets, Capsule, MUPS tablet etc.) show better reproducibility of the drug absorption in the body than single dosage form (Matrix tablet).

10. Direct Compression Of Very High Dose Drug Tablets Using Extremely Compactible MCC, Ceolus™ KG-1000
    12/1/2011
    There are some very high dose tablets in which the drug content is near 1000mg, such as anti-HIV drugs and multi-vitamin supplements. The size of such tablets is often so large that elderly people or small children can’t easily swallow them.