Solving Segregation Effects In Solid-Dosage Form Operations
Understanding segregation and how it is related to drug development cost is at the heart of solving this issue and is the topic of this article.
Early Detection Of Powder Flowability Challenges In Formulation Development Of Solid Dosage Forms
Understanding the impact of powder behavior during pre-formulation will ensure clinically effective products and provide critical process knowledge to design an efficient and reproducible manufacturing procedure.
Is Selecting A CDMO Based On Contract Price Really Saving You Money In The Long Run?
Before you sign on the dotted line, do a little digging to unearth potential costs that could turn your development program into a cash-burning exercise.
Patient-Centric Drug Design — A Clinical And Academic Perspective
Most issues in pediatric drug development arise from the fact that drugs are traditionally developed for adults and not children. Dr. Meyers shares the hurdles and improvements in pediatric drug development.
Why The Shift From Batch To Continuous For Pharma Oral Solid Manufacturing Is Upon Us
There has been intense interest and emphasis being given to the continuous OSD manufacturing process as an alternative or addition to the traditional batch manufacturing process.
How To Increase Regulatory Flexibility And Tablet Production Efficiency
The goal of every pharmaceutical developer is to create quality products that generate consumer satisfaction, require low cost, and have low risk.
The Key To Continuous Manufacturing
Ivo Backx points out that integration of all process automation architectures is essential if continuous manufacturing is to be rolled out successfully.
Accurate Bulk Density Measurement Maximizes Solid Dose Production
The most popular dosage form in the pharmaceutical industry is the compressed tablet. Fully two-thirds of all prescriptions are dispensed in a solid dosage form and half of these are compressed tablets. While it looks simple in its white or colored form, the compressed tablet is a complex mix of the active drug and a host of excipients.
Guest Column: Powder Characterization Techniques For Tableting Applications
Simple to administer, tablets are a feature of every day life. Tablet production has a history dating back more than a century, but retains its ability to frustrate. The drive towards faster production speeds, increasingly potent actives and the adoption of complex tablet structures present modern day tablet manufacturers with significant challenges. Understanding how to manipulate the properties of the blend towards better processing performance and high quality of final product is essential. By Tim Freeman, Freeman Technology
Tutorial: New Technologies Protect Pharmaceuticals Against Counterfeiting
Anticounterfeiting and traceability are different
problems requiring different solutions. On the
one hand, traceability requires standardization
and interoperability among the various manufacturers
and the intervening third parties within the supply chain
up to the dispensing point. By Roland Meylan, AlpVision