White Papers

  1. Driving Efficiency In QC Labs 9/21/2023

    Here, we examine the cause and impact of common errors in Quality Control (QC) labs, the strategy for reducing those errors with an intuitive chromatography system, and more.

  2. Predictive Modeling Of Viscosity Behavior Using Artificial Neural Networks 9/11/2023

    Discover a modeling approach employing artificial neural networks (ANNs) using experimental factors combined with simulation-derived parameters plus viscosity data from 27 highly concentrated (180 mg/ mL) mAbs.

  3. Can Yeast Be The Future Of Efficient Subunit Vaccine Manufacturing? 9/11/2023

    To aid in the manufacturing of new vaccines, Pichia pastoris yeast, a promising protein expression system, could be the perfect solution.

  4. Purity Analysis Methods For Synthetic Prime Editing Guide RNAs 9/8/2023

    Develop a fast, easy workflow for the purity analysis of complex pegRNA molecules along with a robust denaturing technique for pegRNA with high levels of secondary structure.

  5. RFID-Based Unit-Level Traceability: Could It Be The Key To Operational Excellence For Fill-Finish Lines? 9/5/2023

    Radio frequency identification (RFID)-based unit-level tracking solutions for prefilled syringes are poised to help pharma manufacturers address key risks and costly bottlenecks related to the fill-finish process.

  6. Single-Use vs. Stainless Steel Debate In Biopharmaceutical Manufacturing 9/1/2023

    Investigate the advantages and disadvantages of single-use technologies and stainless steel systems with a focus on performance, adaptability, and economics.

  7. Comparing Single-Use To Fixed Bioprocessing Systems 9/1/2023

    Several life cycle assessments have been conducted investigating and characterizing the environmental impact of SUTs compared to conventional fixed systems, leading to results that could inform changes bioprocess system use.

  8. Sterile Filtration And Quality Risk Management 8/31/2023

    During the manufacture of sterile products, process control is essential. Here, we explore the role of filtration for bioburden control in quality risk management and contamination control strategies, EU GMP Annex 1, and more.

  9. Eliminating USP <88> In Vivo Animal Bioreactivity Testing For Polymer Characterization 8/25/2023

    There has been growing awareness about the environmental and ethical implications of plastics used in bioprocessing. The time for a shift to well-studied, proven in vitro cytotoxicity testing is now.

  10. PBPK Modelling For Optimizing Controlled Release Dosage Form Development 8/24/2023

    Examine the benefits of controlled release, the application of PBPK modeling in controlled release formulation development, and how modified release products can be developed to deliver optimal patient outcomes.