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PRODUCTION

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Intensification Strategies For Upstream, Downstream Processes

How do you know if an intensification approach will provide advantages? Three process intensification experts show how various intensification approaches affect outputs using different scenarios.

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Analytical Solutions To Help Accelerate Bioprocessing Success

Unlock the power of data-driven bioprocessing. Discover how advanced analytics can optimize your cell culture process, improve performance, and accelerate success.

43:49 MabSelect PrismA - increased productivity for high demand production with minimal change_web
Strategies And Emerging Technologies For mAb Capture

Explore opportunities with the introduction of high-capacity protein A resins, how and when multicolumn chromatography is beneficial, and how emerging technologies can address bottlenecks.

57:29 Chromatography Lab GettyImages-482759508
Break Free From The Protein A Low-Productivity Paradigm

Protein A resins, with low flow rates and mass transport, lead to low productivity. Discover a solution that removes the bottleneck, offering a disposable alternative for mAb capture.

1:58 Bucket 2
How To Maintain A Nuclease Free Environment During mRNA Production

mRNA are singled-stranded, and their chemistry makes them more susceptible to enzyme degradation than double-stranded DNA. Learn how to maintain a nuclease free environment during mRNA production and purification.

1:02:23 LSC Webinar Bucket
Challenges And Solutions In Aseptic Connection And Disconnection

Progressive biomanufacturing processes require advanced tools to reliably connect and disconnect components. Here, we show a wide range of connection and disconnection options.

33:21 UPLC Columns Fundamentals, Chemistries, And Selected Small-Molecule Applications
UPLC Columns: Fundamentals, Chemistries, And Selected Small-Molecule Applications

Discover the fundamentals of UPLC columns and their diverse chemistries. Learn more about versatility in separating small-molecule analytes using reversed-phase and hydrophilic interaction techniques.

3:02 Thermo
Thermo Fisher Scientific North America Single-Use Technologies Capacity Expansion

Thermo Fisher Scientific is expanding our single-use manufacturing network globally. Some of the largest investments are taking place at our existing Logan, Utah, and Millersburg, Pennsylvania, sites. We are adding space for clean rooms for the manufacturing and assembly ...

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mAb Up- And Downstream Process Intensification Strategies

Discover how to reduce monoclonal antibody (mAb) manufacturing time and costs through process intensification. Learn about continuous perfusion, ultrahigh cell density banks, and more.

2:36 oligosynt Synthesizer
Key Functions Of The ÄKTA Oligosynt Synthesizer

Discover a compact, fully automated oligonucleotide synthesizer for robust, scalable process development. Learn how it can help establish a robust and reproducible oligo synthesis process.

1:00:15 How To Plan For Trouble-Free Filter Validation
How To Plan For Trouble-Free Filter Validation

Watch to learn when filter validation should be performed, what is required from an end user and laboratory testing perspective, and how to achieve first-time success for various drug products.

3:53 Thermo2
Thermo Fisher Scientific China Single-Use Technologies Capacity Expansion

Thermo Fisher Scientific is expanding our single-use manufacturing network globally. With continuous growth in China’s population, we have seen an increase in demand for human therapeutics and vaccines and an even greater need for investment in public health and saf...

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Nitrosamine Impurities Deadline: Are Your Products Compliant?

Learn how to select an experienced nitrosamine mitigation provider and how a tailored, quantified strategy can help you bring your product into compliance while maintaining control of the process.

3:46 Scientists Viewing Tablet GettyImages-1370154332
Meet The Experts: Part 3 - Chemometrics And Model Building

Watch part 3 of this 4-part interview series to learn about chemometrics and model building from expert Johan Cailletaud.

0:31 BioSMB Multi-Column Chromatography
Transform Your Chromatography Processes With An Innovative Approach

Learn how to achieve better resin utilization, minimize disruption to existing methods, and align your strategy with unique process goals.

0:45 GettyImages-1284791212 environment, sustainability
Reimagine Sustainability In Bioprocessing

Achieving sustainability in bioprocessing labs presents distinct challenges. Learn how to reduce your environmental footprint while maintaining efficiency and avoiding extensive re-validation efforts.

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A Conceptual Overview Of The BioSMB MCC Platform

In this video, our technology expert Jason Forte describes how the BioSMB system offers 3-5 fold increase in productivity, yielding up to 80% savings on chromatography resin costs with minimal disruption to the accepted ways of doing chromatography today.

33:18 Cytiva
Strategies For Scaling Up mRNA Manufacturing

The clinical promise of mRNA therapeutics and vaccines is clear, but compared to monoclonal antibodies or viral vectors, their novelty also brings new challenges to the manufacturing process.

21:58 How To  Develop An Efficient Downstream Purification Process For Bispecific Antibodies
How To Develop An Efficient Downstream Purification Process For bsAbs

Bispecific antibodies (bsAbs) have gained increasing interest in recent years. Learn how to develop an efficient downstream purification process for a cancer immunotherapy bsAb.

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Bioburden And EU GMP Annex 1: Risk Assessment, Reduction, And Testing

Experts on regulation, filtration, sampling, and quality control discuss risk assessment and filtration-based strategies to reduce bioburden.

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How mRNA Manufacturers Disrupt The Industry

Learn how biopharmaceutical companies can apply proven strategies to overcome hidden complexities in mRNA production, and discover solutions that can help you rapidly design and build a SU facility.

59:41 Singota - CDMO Perspectives Splash
Client Sustainability Directives — CDMO Perspectives

Gain a deeper understanding of current directives and metrics to equip your team with the knowledge necessary to navigate the evolving landscape of sustainability.

5:02 Thermo Fisher Scientific Suzhou, China Manufacturing Site Capabilities
Thermo Fisher Scientific Suzhou, China Manufacturing Site Capabilities

Watch this video to learn more about this manufacturing site capabilities, quality management systems, PPI implementation, product expansion, assurance of supply and lead times.

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Scaling Up: Increasing Production Capacity While Reducing Costs

Medical device companies must meet the demand plan for their devices while managing production costs. Gain valuable insights for scaling up production capabilities efficiently and cost-effectively.

4:38 Thermo Fisher
Advanced Granulation Technology (AGT) Cell Culture

This video is an overview of the most advanced media format available for cell culture - AGT.  A granular dry media format produced through a technologically advanced process which allows manufacturing of complete formulations in a dry format. It can be used in both ...

2:36 AustinPx - Kinetisol
Technology To Overcome Absorption Hurdles And Solubility Limitations

For poorly soluble drugs, overcoming absorption hurdles can hinder development. Explore a solution that empowers researchers to overcome solubility limitations and accelerate drug development.

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Improve The Bioavailability Of Poorly Soluble Drugs

KinetiSol is a fusion-based, solvent-free process that utilizes frictional and shear energies — in a fraction of the time of other amorphous solid dispersion technologies.

3:10 MCC vs batch
How To Select Your DSP Chromatography Technology

Watch to explore the differences between the conventional single-column batch method and the multi-column approach for mAb capture.

3:32 Thermo3
Thermo Fisher Scientific EMEA Single-Use Technologies Capacity Expansion

Thermo Fisher Scientific is expanding our single-use manufacturing network globally. Our Cramlington, UK site has expanded clean room space and invested in chamber manufacturing equipment for our BioProcess Containers and fluid transfer assemblies. Quality systems and pro...

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Slurry Bin Functionality With The DAC Ergo

Check out how our optional stainless-steel bin works in conjunction with the DAC Ergo to capture spent media.