Newsletter | March 20, 2025

03.20.25 -- Addressing Challenges In Automated Visual Inspection Of Lyophilized Vials

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INDUSTRY INSIGHTS

Shaping The Future Of Solid Dose Manufacturing With Hot Melt Extrusion

Enhance your drug development strategies today and master hot melt extrusion by learning about excipient selection, equipment setup, novel screening tools, and process optimization.

Building Control Strategies: It's Time To Go Digital

Digital control strategies in pharma enhance product quality, regulatory compliance, and efficiency by leveraging real-time monitoring, automated documentation, and Quality by Design (QbD) frameworks.

Legal Changes To Fortify Environmental Risk Assessment

A new EU directive may require stricter environmental risk assessments for pharmaceuticals, impacting marketing authorization. Examine updated guidelines already in effect that pose new challenges.

Building Complexity In Organoid Models

Learn about the impact and advancing use of organoids on basic and translational research, as well as their potential in areas such as disease modeling and drug screening.

The Write Side Of AI: Augmenting Capabilities, Not Replacing Them

Discover how AI applications in medical writing are in their infancy, and how the technology suffers several shortcomings including plagiarism, copyright infringement, and misinformation dissemination.

The Importance Of A Multifaceted Approach To Containment

Risk assessment is integral to manufacturing processes, particularly in drug production, and having effective containment strategies can help identify potential hazards and ensure worker safety.

Development Of Next Gen Sustained Release Solutions For Pain Management

A TheraPEA polymer based injectable formulation designed to deliver the same dose of Triamcinolone Acetonide (TAA) as in Zilretta has shown promising results in a series of pre-clinical studies.

De-Risking Early Phase Micronization With Integrated Solid Form Selection

Review a case study describing the selection of the optimal solid form of an API designed for pulmonary administration through the pulmonary route.

Supplier Quality And The True Cost Of Recalls

Recalls can cost millions (or even billions) and threaten a company’s public perception. Find out how to minimize recall costs and enhance compliance with effective quality management strategies.

Data Collaboration Driving CDMO Excellence, Product Innovation

Read about how CMOs and CDMOs who do not address the rising demand from life science clients for greater visibility in the manufacturing process risk falling behind.

How To Avoid Sticking And Picking In The Tableting Industry

Uncover strategies to mitigate sticking and picking risks in the tablet industry, and learn how you can foster improved tablet production processes to ensure higher quality and consistency.

Best Practices For Chromatography Column Packing

Proper packing for resin is crucial to prevent issues like cracking or channeling which can lead to process disruptions and product loss.

Innovative AI-Driven Solutions To Address The Growing Complexity Of APIs

Computer-aided synthesis planning (CASP) can mitigate the impact of rising complexity. Delve into the discussion of the award-winning AI and data that propel a leading predictive retrosynthesis technology.

A Comprehensive Solution For Critical Sample Analysis

See how Germfree Laboratories overcame challenges for the Royal Canadian Mounted Police by designing a mobile lab with advanced biocontainment and state-of-the-art communication systems.

Reduce Drug Manufacturing Downtimes With Accumulator Technologies

How can the performance of a production line be improved while minimizing downtime? One effective approach is to use accumulators between upstream and downstream machines.

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With over 75% of U.S. hospitals facing medication shortages, decentralized manufacturing offers a vital solution by bringing drug production closer to patients. This webinar explores how Germfree and On Demand Pharmaceuticals’ collaboration enables on-site, agile medicine production. Learn how localized manufacturing enhances supply reliability, regulatory compliance, and patient access through cutting-edge cleanroom and compounding technologies. Click here to learn more.

FEATURED EDITORIAL

Addressing Challenges In Automated Visual Inspection Of Lyophilized Vials

Manual inspection is inefficient. Lyophilization stabilizes biologics, vaccines, and injectables, but automated systems can struggle with the variability of lyo cake structures. Examine key technological advancements that are coming to the forefront to address these issues.

SOLUTIONS

Scientist Spotlight: Luigi Bellone

Wipes For Critical Environments

Capacity Update January 2025: Fill/Finish

Container Closure Integrity Testing Services

A Guide To Cleaning RNA Contamination

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Webinar: Do Not Bear Cross Contamination in the Pharmaceutical Industry – Prevent it

Save the date to explore how process optimization plays a key role in achieving effective critical cleaning in pharmaceutical manufacturing. Learn how optimizing cleaning chemistry, selecting the right detergents, and refining process parameters can prevent cross-contamination, improve efficiency, and ensure product quality. Hear case studies on enhancing compliance, reducing costs, and meeting regulatory standards for safe, quality production. Click here to learn more.

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