Article | June 2, 2022

An Insoluble Problem? Overcoming Oral Drug Solubility Challenges With Functional Polymers

Source: Evonik Corporation

By Dr Thomas Endres, Head of New Products & Materials, Evonik Corporation

Evonk DA-HealthCare Tablets 13 5 2019 Macro mas-foto_100

Almost half of currently marketed drug products, and around 90 percent of those in clinical development are associated with poor drug solubility or permeability. This article is part one of a two-part series on solubility enhancement. Here we will discuss the basics of solubility enhancement and the formulation and manufacture of products that enhance solubility. We will also address common questions on the topic.

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