Application Note

Application Of The Finesse Glass Bioreactor For Fermentation Of Saccharomyces Cerevisiae

Source: Thermo Fisher Scientific

This application note describes the cultivation of Saccharomyces cerevisiae cells in the Finesse glass vessel bioreactor with a maximum working volume of 2.0 L. Using the chemically defined medium D, it was possible to produce up to 5.33 g∙L-1 of dry biomass from 40 g∙L-1 glucose. The cells were grown under aerobic conditions with a specific growth rate up to 0.4 h-1 and a yield coefficient for the biomass of 0.13 g cdw·g gluc-1By Nadezda Perepelitsa, Stephan C. Kaiser and Dieter Eibl