Brochure | January 23, 2020

Aspetic And Non-Sterile Glove Boxes And Containment Systems For HPAPI Processing

As more information becomes available about the toxicity and potency increases across the marketplace, the need for personnel and/or product protection grows. Flow Sciences is the world leader in sophisticated containment to meet these challenges with proprietary engineering and design that allows for the creation of validated engineered solutions.


Exposure to APIs (Active Pharmaceutical Ingredients) and other potent compounds pose a danger to employees that must work with these materials. Pharmaceutical, biopharmaceutical and chemical companies are working with increasingly more potent and hazardous compounds to produce the medicines and high tech products needed
in our modern society.

In addition, these products need to be protected from cross contamination while they are processed. Clean, contamination-free work areas must be provided to protect the product and personnel.

Stringent permissible exposure limits are extremely low for operator protection and for contamination control. This presents engineering challenges for equipment manufacturers to meet these strict conditions.


Flow Sciences, Inc. has been manufacturing solutions for these problems for three decades. We began in the early 90’s building the Vented Balance Safety Enclosure which soon became the standard in the pharmaceutical industry to provide worker protection from potent compounds used in drug discovery. Following this, the industry began to ask for solutions for other containment issues they were experiencing. This has evolved into our web database called “TaskMatch,” which features hundreds of unique custom designs that customers can select as a solution to their containment problem.

During our evolution, we have designed a product line to enable work with potent compounds under controlled humidity and low oxygen environments. It was necessary for FSI to develop electronic control instrumentation to control these processes in order to facilitate the products.

In the past five years, a program has been launched to produce glove boxes that meet cGMP requirements that will have interior clean environments with exhaust filtered air that is scrubbed to prevent contamination of individuals and environments. These products are being used in the exciting breakthrough medical research in ADC (Anti-Body Drug Conjugates) to develop and manufacture anti-cancer drugs, oncology compounds and Nano pharmaceuticals. This booklet is dedicated to high performance glove boxes for many applications across the industry.

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