FEATURED ARTICLES

• Flow Science Fume Hood Builder
• Understanding The Importance Of Powder & Vapor Containment

  Have you considered the safety of your work environment’s air? Across industries, employers are determining how to detect inhalation hazards and, if present, how to protect employees from them.

• Flow Sciences Introduces Innovative Online “Containment Process Builder” Tool For Life Sciences

  Flow Sciences, Inc., a leading provider of containment systems for laboratory, pilot plant, and manufacturing has launched the Containment Process Builder (CPB), an online visualization and documentation tool that allows the user to build their very own containment process and visualize the combination of products in real-time. The purpose behind the Containment Process Builder is to provide a collaborative, interactive online builder that accelerates design, process, and equipment input during the concept stage of development.

• Evolving Containment In Pharma Manufacturing Facilities

  Here, we characterize the new production directions in pharmacy and describe the flexible equipment to improve pharma efficiency, purity, and production safety in the coming decade.

• Vibration Isolation For Enclosures

  In analytical environments, precise weighing takes place inside containment where powders do not escape. Read on to examine the effectiveness of three vibration isolation strategies.

• Facilitating Flexibility In A Dynamic Laboratory Work Environment

  Supplying a fiberboard mockup allows a customer to make additional considerations before finalizing the design needed to enclose several processes requiring product manipulation in two or more “phases”.

• HPAPI Processing And Drying Suite For Operator And Product Protection

  A two-part enclosure consisting of a single pass airflow glove box enclosure and a nitrogen purge enclosure was designed to provide protection to the operator and product.

• HPAPI Containment Solution For A Benchtop Vacuum Oven Process

  Providing personnel protection when working with highly potent active pharmaceutical ingredients (HPAPI) is very tricky. In this case, a containment solution was designed for a benchtop vacuum oven process.

• Oncology Workstation With HPAPI Transfer For Personnel Protection

  The Oncology Workstation with EziDock CSV6 HPAPI Transfer was designed to provide personnel and product protection while working with powder substances. 

• Modular Containment Unit Solution For A Genevac EZ2 Elite Evaporator

  Read how a custom designed modular containment unit provided the solution needed to allow for transfer of materials post-manipulation into a separate, connected balance enclosure for weighing.

• The API Process Development System For Personnel And Product Protection

  The API Process Development System was designed to provide personnel and product protection when working with powder and liquid substances. 

• Glovebox Design Encloses Milling Processes

  A manufacturer required a glovebox that would enclose milling processes done by either a Fitzmill L1A or a Quadro Comil. Read how the design features allowed the operator the access and flexibility that they needed while achieving the containment requirements that were required.

• Mini-Spray Dryer Encloser Solution For Pharmaceutical Application

  A client required the design and build an enclosure that could house the Buchi B-290 Mini-Spray Dryer during process. The solution offered containment down to less than one microgram per cubic meter.

• Toxic Treatments: Controlling Exposure Risks In ADC Manufacturing

  The potency and effectiveness of the ADCs are dependent upon engineered nanoparticles (ENPs), but little is known about the environmental and human health hazards posed by ENPs.

• Evaluating A Chemical Fume Hood For Containment Of Solids, Liquids, And Vapors Using ASHRAE 110, HAM, And ISPE Methods

  Originally designed around 350 years ago to contain accidents and prevent bad odors in the laboratory, the fume hood has become a device that can routinely produce control levels of vapors down to the part-per-billion level. In this study, Flow Sciences chose to meld existing techniques centered around ASHRAE 110 with widely-accepted particulate containment measurement techniques. The Flow Sciences fume hood, when used in conjunction with good lab practices, is capable of providing workers with the protection they need for applications using solids, liquids and gases.

• Validation Of A Glovebox Workstation

  Many existing research labs, pharmaceutical and biopharmaceutical manufacturers, and contract manufacturing organizations (CMO’s) are not designed nor are they equipped with the engineering controls to safely handle the manufacture of ADC’s. The safe manufacture of ADC’s requires more modern facilities, equipment, and engineering controls as well as programs, practices, and procedures to adequately protect the operators and the work environment. Read the steps that must be taken to consider a glovebox workstation fully validated to manufacture ADCs safely.

• Critical Considerations When Selecting A Vented Balance Enclosure

  This paper discusses the primary benefits of the vented balance enclosure, which is critical to the safe and effective weighing of potent powder compounds, APIs, and nanomaterials. 

• Manufacturer Finds Solution For Transporting HPAPI Product with Containment

  Containment enclosure solution for an analytical weighing and solution-preparation operation involving HPAPI in powder form allows manufacturer to successfully transfer product from an enclosure to another enclosure.

• Shipping, Assembling, And Installing Bulky Exhaust Equipment In A Lab

  Though delivering, unloading, staging, and assembling are required steps in all lab construction, there are design aspects of lab equipment that can contribute to its successful field installation.

• Getting What You Need In A Laboratory Hood

  Understand what information you should be communicating to the manufacturer to ensure you get the best lab containment equipment, built correctly the first time.

• Venting Fume Hood Base Cabinets — A Better Way

  Frequently, companies have used fume hood exhaust to ventilate hood base cabinets. There is both the need for this practice and the designs for them are frequently not well thought-out. 

• 10 Worst Containment Engineering Mistakes

  Engineering is a process to develop a design to solve a problem. In the world of containment engineering, careful premeditation is important to the completion of a successful engineering project.

• The Keys To Superior Containment In Compounding Applications

  This paper reviews why very bad things happen when either quantity or purity of Highly Potent Active Pharmaceuticals is not properly maintained during the compounding process. 

• 10 Considerations For Balance Stability

  Stability of your weighing balance is paramount when it comes to collecting reliable data. Depending on the problem, taking obvious action for a seemingly obvious solution may not result in success.

• Common Fume Hood Containment Problems

  While there are “bad” fume hoods, anything wrong with the entire system (exhaust fan, ductwork, building configuration, regulative dampers) may cause a lack of containment in a hood.

• Containment Liability: Choosing Assurance Or Insurance

  Engineering controls designed to mitigate exposure and create separation between the operator and toxic material are available in many forms, all with their own unique advantages and risks.

• The Challenges Batch And Continuous Manufacturing Bring To Containment

  There are two basic models of pharma manufacturing: batch and continuous. Here, we compare the two and examine the challenges they bring to containment product design.

• Five Tests For Pharmaceutical Containment

  We analyze and explain different containment methods and help determine which would be most beneficial for your first (or next) containment device to ensure personnel protection.