Atmospheric Control Module: Safe, Automatic, And Pressurized Containment For HPAPIs

When working with high-potency active pharmaceutical ingredients (HPAPIs), maintaining consistent negative pressure containment is vital for operator safety and GMP compliance. Manual monitoring introduces variability that automated systems are specifically designed to eliminate.

The Atmospheric Control Module from ILC Dover provides fully automated pressure control for flexible isolator environments, targeting a precise set point of -15 Pa. The system continuously monitors internal pressure and responds immediately to any breach, adjusting fan speed to restore containment without operator intervention. This automated response cycle reduces exposure risk and supports consistent GMP manufacturing outcomes.

The module is compatible with both air and nitrogen supply, making it suitable for oxygen-sensitive or potentially explosive materials. Its portable, compact design allows integration with existing or new flexible isolators, and frames can be retrofitted with push-push HEPA filters for added flexibility across laboratory and manufacturing settings.

Unlike hard-wall isolators or laminar flow hoods, the flexible isolator configuration supports a generous range of operator motion, reducing fatigue during extended contained handling tasks. Download the product flyer below to learn more.