Brochure | June 16, 2021

CentriPAK BioProcess Container - Rapid Harvest Without Clogs In Depth Filtration Methods

When harvesting cell cultures with high density ( > 250x10^6 cells/mL) or high turbidity ( > 3000 NTU), depth filters can quickly clog and bring the entire process to a standstill. In addition to creating delays, replacing the clogged filters is messy and introduces risks of contamination along with reduced yield.

Use of unique, single-use Thermo Scientific™ CentriPAK™ BioProcess Containers (BPC) and the Thermo Scientific™ Sorvall™ BIOS 16 Centrifuge is an excellent method to pre-clarify supernatants prior to depth filtration or downstream processing. This method reduces overall processing time by eliminating pre-setup and post-cleaning steps as well as avoiding in-process clog-based delays. The sterilized, closed system ensures confidence in culture yield and purity. In this example, we harvest supernatant from a 50 L mammalian culture.

access the Brochure!

Get unlimited access to:

Trend and Thought Leadership Articles
Case Studies & White Papers
Extensive Product Database
Members-Only Premium Content
Welcome Back! Please Log In to Continue. X

Enter your credentials below to log in. Not yet a member of Pharmaceutical Online? Subscribe today.

Subscribe to Pharmaceutical Online X

Please enter your email address and create a password to access the full content, Or log in to your account to continue.

or

Subscribe to Pharmaceutical Online