Complementing Routine Peptide Monitoring Using The ACQUITY QDa Mass Detector

By Robert E. Birdsall, Eoin F.J. Cosgrave, and Sean M. McCarthy, Waters Corporation

This application note is designed to showcase the powerful capabilities of the ACQUITY QDa Detector as a complementary, orthogonal detection technique. By integrating both optical (UV) and basic mass spectral data into a unified analytical workflow, the system enhances the depth and reliability of peptide analysis. Using a known peptide mixture, the application demonstrates how the ACQUITY QDa Detector can seamlessly combine UV detection with mass spectrometry to offer a more comprehensive understanding of sample composition. This dual-detection approach not only improves data confidence but also streamlines laboratory workflows by reducing the need for separate analyses.

If you're looking to elevate your analytical capabilities and streamline your workflows, explore how the ACQUITY QDa Detector can transform your lab's performance.