Comprehensive Workflow For Quantitative Bioanalysis Of Large Peptides And Proteins: A Case Study Of The GLP-1 Receptor Agonist, Semaglutide, In Plasma

By Samantha Ferries, Suraj Dhungana, Robert S. Plumb, and Amy Bartlett, Waters Corporation

Light scattering is a powerful analytical technique that plays a crucial role in understanding the structural integrity, aggregation behavior, and overall stability of GLP-1 analogs—key components in the treatment of type 2 diabetes and obesity. By examining how light interacts with these molecules, researchers can gain deep insights into their physical properties, which helps to optimize drug formulations for improved bioavailability and therapeutic performance. This not only enhances the efficacy of treatments but also contributes to the development of more reliable and patient-friendly medications.

If you're involved in drug development or pharmaceutical research, now is the time to explore how light scattering can elevate your formulation strategies. Discover the potential of this technology to transform your approach.