Ensuring Integrity: Testing Viscous Biologics In Pre-Filled Syringes With E-Scan® HVLD

As self-administered therapies become more common, pre-filled syringes are increasingly used for biologics, yet their complex sealing points and fragile materials make container closure integrity critical. Viscous, protein-based formulations pose additional challenges for inspection, requiring advanced, deterministic methods. High Voltage Leak Detection (HVLD) offers a proven solution by detecting breaches through changes in electrical resistance. Find out how MicroCurrent HVLD technology ensures integrity for polymer and glass syringes filled with gel-like biologics. By establishing a statistical baseline and detecting micro-defects as small as 5 microns, the system delivers robust, repeatable results that meet USP <1207> standards.

Learn how HVLD safeguards sterility and patient safety for sensitive drug products.