By Dr. Matthias Wiehn, Global Product Manager Oral Excipients, Evonik
The market for oral drug products with an immediate release profile continues to move towards the development of more complex dosage forms that are designed to address specific functional or application requirements. In almost every case, the goal is to create oral drug products with functional coatings that are so easy to manufacture and administer that they will optimize patient acceptability and brand preference.
Evonik has been partnering with pharmaceutical companies to overcome a range of development and manufacturing challenges associated with immediate release dosage forms over many years. While each formulation is different based upon factors such as the API, processing method and patient population, we’ve found that customers most commonly want solutions to some combination of the following five key challenges.