White Paper

Five Of The Most Useful Transformations In Modern Organic Synthesis

By Dr. Paolo Braiuca, Director, Global Market Development Laboratory Chemicals Division – Fine Chemical Products


Incredible creativity has gone into translating the decades of chemical knowledge since World War II, allowing new discoveries from a toolbox of efficient reactions, and enabling the synthesis of very complex, multi-functional molecules. While new inventions occasionally provide leaps forward that profoundly change the chemical landscape, innovation is driven by the sum of small steps in the applications and reaction conditions, often inspired by research in adjacent fields.

The five most widely used reactions in medicinal chemistry include a mix of “traditional” reactions found in year one chemistry classrooms and sophisticated newer transformations: aromatic nucleophilic substitution (SNAr), amination/alkylation of amines, amine protection and deprotection, amide synthesis, and C-C cross-coupling.

access the White Paper!

Get unlimited access to:

Trend and Thought Leadership Articles
Case Studies & White Papers
Extensive Product Database
Members-Only Premium Content
Welcome Back! Please Log In to Continue. X

Enter your credentials below to log in. Not yet a member of Pharmaceutical Online? Subscribe today.

Subscribe to Pharmaceutical Online X

Please enter your email address and create a password to access the full content, Or log in to your account to continue.


Subscribe to Pharmaceutical Online