Fully Automated Cell Culture Passaging And Expansion Using Decision Making-Based Image Analysis

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Cell culture is a labor-intensive task that demands meticulous attention to detail and imposes substantial time commitments on scientists throughout the week, including weekends. The process requires constant monitoring and intervention to ensure optimal growth conditions and prevent contamination. Automation offers a promising solution to alleviate these time-sensitive and highly routine tasks from scientists, significantly reducing human error and inconsistencies associated with manual processes. While automated liquid-handling systems have been developed to manage complex processes using liquid-handling devices, fully automating the entire cell culture process presents a greater challenge.

Automated decision-making systems can facilitate not only media exchange and passaging but also enable comprehensive cell culture control without the need for scientists to be physically present in the lab. This advancement allows for continuous monitoring and adjustment of growth conditions to ensure consistent and reliable cell culture passaging and maintenance with minimal user interaction.

Explore the methods and technologies that enable consistent and reliable cell culture passaging and maintenance, as well as how leveraging imaging and automated decision-making can aid scientists in achieving higher accuracy and reproducibility in cell culture processes.