FEATURED ARTICLES

• Mitochondrial Toxicity Application Guide

  Mitochondria are vital for energy conversion, calcium signaling, metabolism, and apoptosis regulation. This guide details how to analyze mitochondrial toxicity and plan experiments.

• Speeding-Up Analysis And Fast-Tracking mRNA Development

  mRNA therapeutics have the potential to address a variety of diseases, and understanding mRNA molecules and access faster analytical solutions are crucial elements for the rapid development of these therapies.

• Streamlining 3D Cancer Assays With Automated Innovations

  Gain insight into the use of 3D cultured cancer models in the search for new therapies for complex diseases like cancer.

• Enabling Rapid Cell Line Screening To Reach Results Faster

  The development of mAb based therapeutics can be a time-consuming and costly process of cell line establishment, but high-throughput screening and automated methods for IgG quantification can help.

• Eliminating Analytical Bottlenecks And Streamlining Drug Discovery

  Advanced analytical methods play a crucial role in drug development pipelines by providing accurate data for informed decision-making. However, the increasing complexity and volume of data present challenges in managing and analyzing it effectively.

• What Is The FusionOptics Technology?

  Learn about stereo microscopes that combine high resolution and depth of field to provide a superior 3D perception of samples.

• Key Factors To Consider When Selecting A Stereo Microscope

  Explore a comprehensive guide to choosing the right stereo microscope for your application, including which key factors you should consider and analyze.

• Spatial Biology: Learning The Landscape

  Biological research is changing with a growing understanding of spatial biology, including the organization and interaction of molecules, cells, and tissues in their native spatial context.

• Which Microscope Camera Is Right for You?

  What are the key factors to consider when choosing the right microscope camera for your system and experimental needs?

• Five Inverted-Microscope Advantages For Industrial Applications

  Learn about five of the advantages of using an inverted microscope for sample observation and industrial applications, as opposed to an upright microscope.

• Building Complexity In Organoid Models

  Learn about the impact and advancing use of organoids on basic and translational research, as well as their potential in areas such as disease modeling and drug screening.

• Industrial-Scale Organoid Production: Challenges, Advantages And Solutions

  Organoids, 3D models replicating human organs, are a growing topic of interest for researchers as they offer invaluable advantages, but come with several challenges.

• The Role Of CRISPR Cas9 Plasmids In Gene-Editing

  Plasmids are crucial for CRISPR-Cas9 gene-editing technology, and their role in CRISPR is expected to evolve with ongoing research.

• High Sequence Coverage And Confident PTM Analysis Of Biotherapeutics Using An EAD-Based Workflow

  Explore how a streamlined, EAD-based middle-down workflow can achieve consistent high sequence coverages of mAb subunits and confident PTM analysis in a single injection.

• Monitoring And Determining The Cause Of Antibody Discoloration Using cIEF And EAD

  View a study which provides additional insight into the factors that govern the discoloration of protein therapeutics and the role of AGEs in color change.

• EAD-Based Middle-Down Workflow Analysis

  How can a single-injection, EAD-based middle-down workflow leverage accurate mass measurement, information-rich EAD fragmentation and automated data analysis to offer confident sequence confirmation.

• CE-SDS Analysis Of Etanercept Using The BioPhase 8800 System

  In this study, a system with multi-capillary capabilities was used to analyze etanercept by bapillary electrophoresis-sodium dodecyl sulfate (CE-SDS).

• mRNA-LNP Nucleic Acid Assessment From Distinct Formulations

  Review a showcase of a high throughput robust analysis for nucleic acid integrity and size assessment of mRNA-LNP samples using a multi-capillary system and purity and integrity analysis kit.

• Molecular Weight Confirmation For Length, Integrity And Impurity Analysis Of A 70-Mer Oligonucleotide

  Explore a workflow used to determine the molecular weight and analyze the purity of a 70-mer DNA sequence with a 3’ dT overhang.

• Purity Analysis Methods For Synthetic Prime Editing Guide RNAs

  Develop a fast, easy workflow for the purity analysis of complex pegRNA molecules along with a robust denaturing technique for pegRNA with high levels of secondary structure.