FEATURED ARTICLES

• Using dSEC-7 Column For Separation And Length Determination Of mRNA

  mRNA analysis depends on methods that can separate broad size ranges. Learn how retention time can help estimate transcript length and complement capillary electrophoresis workflows.

• What Is Size Exclusion Chromatography (SEC)?

  Aggregation can compromise mAb quality at many stages of development. Learn why size exclusion chromatography is a trusted approach for detecting aggregates and supporting confident characterization.

• Peptide Mapping Of Adeno Associated Virus Capsid Proteins

  Peptide mapping helps reveal AAV capsid protein identity, sequence coverage, and potential modification patterns, giving gene therapy teams a clearer view of viral protein quality across workflows.

• Native RPLC For ADCs: How Column Hydrophobicity Shapes DAR Separation

  ADC characterization does not have to be overwhelmed by complex intact MS profiles. Smart column selection can improve separation, clarify critical quality attributes, and make ADC analysis easier.

• Sample Clean-Up After N-Linked Glycan Release And Labeling

  Glycan profiling starts with effective clean-up. See how comparable recovery across key labeled glycans and sialylated glycan groups can support confident analysis while helping labs manage costs.

• What Is Drug Antibody Ratio (DAR) And How It Relates To Biotherapeutics?

  DAR is a key quality attribute that shapes ADC potency, safety, stability, and developability. Learn why accurate measurement and control are essential as ADC pipelines expand and expectations rise.

• HPLC Method Development For Monoclonal Antibody Aggregates With SEC

  SEC for monoclonal antibodies is not always as simple as choosing a column and running PBS. Secondary interactions can affect recovery, making thoughtful method development essential.

• Protein Purification By HPLC: Methods, Benefits, And Best Practices

  Read about how HPLC protein purification enables precise, reproducible isolation of target proteins from complex mixtures while preserving structure and activity—supporting high-purity workflows.

• Exploring Protein Purification Methods: Essential Techniques

  Effective protein purification starts with matching the method to the molecule and the application. Learn how scale, throughput, purity goals, and empirical optimization influence successful recovery.

• What Will It Take To Make MCED And MRD A Reality?

  Cancer mortality is declining, but the need for earlier action remains. Gain insight into how MCED and MRD are advancing cancer detection and surveillance, helping clinicians identify disease sooner.

• How To Power MRD Assessment And Multi-Cancer Detection Research

  New advances in MCED and MRD monitoring are transforming cancer care. Fueled by NGS insights, see how these approaches are shifting treatment decisions toward more proactive strategies.

• Advances In Whole Exome Sequencing

  Whole exome sequencing is accelerating genetic discovery. Learn how it enables biomarker detection, supports cancer research, and expands opportunities for scalable, future-ready genomic analysis.

• Real-Time PCR: Design, Analysis, And Troubleshooting

  Build stronger qPCR assays by delving into how to troubleshoot common issues, improve reproducibility, and confidently quantify gene expression across a wide range of experimental conditions.

• Direct Amplification Of Research Samples

  Skip time-consuming extraction steps and achieve reliable qPCR results. Direct amplification methods help researchers detect respiratory pathogens more efficiently across saliva and nasal samples.

• Direct Amplification Of Cell Culture Samples

  Skip extraction and move straight to amplification with a streamlined qPCR workflow. Achieve comparable performance across multiple targets while reducing costs and saving time.

• qPCR Amplification Of Human Gastrointestinal Samples

  Residual inhibitors in GI-derived DNA can hinder qPCR performance. An optimized approach improves inhibitor tolerance and enables earlier target detection, delivering more reliable amplification.

• NGS Identification Of Internal Tandem Duplications In FLT3

  Accurately identifying genetic duplications in leukemia requires more than conventional sequencing. See how advanced enrichment and analysis approaches enable deeper insight into variant structure.

• Next Generation Sequencing Guide

  Learn how sequencing strategy, library prep, and data quality considerations shape outcomes in modern genomics. Clear insights help optimize workflows across a wide range of sequencing applications.

• Navigating Regulatory Barriers For CRISPR Gene Editing Therapies

  Bringing CRISPR therapies to market requires navigating complex global regulations. Learn how strategic planning, risk assessment, and manufacturing alignment can streamline development.

• Get More From Less: AMP Chemistry Outperforms Hybrid Capture

  Sequencing performance can drop quickly with low-quality, low-input FFPE DNA. Gain insight into how one approach helps labs minimize repeats and maintain more consistent results.