FEATURED ARTICLES

• What Is The FusionOptics Technology?

  Learn about stereo microscopes that combine high resolution and depth of field to provide a superior 3D perception of samples.

• Key Factors To Consider When Selecting A Stereo Microscope

  Explore a comprehensive guide to choosing the right stereo microscope for your application, including which key factors you should consider and analyze.

• Spatial Biology: Learning The Landscape

  Biological research is changing with a growing understanding of spatial biology, including the organization and interaction of molecules, cells, and tissues in their native spatial context.

• Which Microscope Camera Is Right for You?

  What are the key factors to consider when choosing the right microscope camera for your system and experimental needs?

• Five Inverted-Microscope Advantages For Industrial Applications

  Learn about five of the advantages to using an inverted microscope for sample observation and industrial applications, as opposed to an upright microscope.

• Industrial-Scale Organoid Production: Challenges, Advantages And Solutions

  Organoids, 3D models replicating human organs, are a growing topic of interest for researchers as they offer invaluable advantages, but come with several challenges.

• The Role Of CRISPR Cas9 Plasmids In Gene-Editing

  Plasmids are crucial for CRISPR-Cas9 gene-editing technology, and their role in CRISPR is expected to evolve with ongoing research.

• High Sequence Coverage And Confident PTM Analysis Of Biotherapeutics Using An EAD-Based Workflow

  Explore how a streamlined, EAD-based middle-down workflow can achieve consistent high sequence coverages of mAb subunits and confident PTM analysis in a single injection.

• Monitoring And Determining The Cause Of Antibody Discoloration Using cIEF And EAD

  View a study which provides additional insight into the factors that govern the discoloration of protein therapeutics and the role of AGEs in color change.

• EAD-Based Middle-Down Workflow Analysis

  How can a single-injection, EAD-based middle-down workflow leverage accurate mass measurement, information-rich EAD fragmentation and automated data analysis to offer confident sequence confirmation.

• CE-SDS Analysis Of Etanercept Using The BioPhase 8800 System

  In this study, a system with multi-capillary capabilities was used to analyze etanercept by bapillary electrophoresis-sodium dodecyl sulfate (CE-SDS).

• mRNA-LNP Nucleic Acid Assessment From Distinct Formulations

  Review a showcase of a high throughput robust analysis for nucleic acid integrity and size assessment of mRNA-LNP samples using a multi-capillary system and purity and integrity analysis kit.

• Molecular Weight Confirmation For Length, Integrity And Impurity Analysis Of A 70-Mer Oligonucleotide

  Explore a workflow used to determine the molecular weight and analyze the purity of a 70-mer DNA sequence with a 3’ dT overhang.

• Purity Analysis Methods For Synthetic Prime Editing Guide RNAs

  Develop a fast, easy workflow for the purity analysis of complex pegRNA molecules along with a robust denaturing technique for pegRNA with high levels of secondary structure.

• Enabling Digital Innovation To Transform Cell Line Development

  Establishing an integrated, tailored data management strategy is core to getting the cell line development journey right.

• Structural Characterization Of The Cationic LNP Component

  Gain a deeper understanding of how EAD is used when characterizing ALC-0315 and its impurities, as well as identify the nature and site of chemical alterations in ALC-0315 resulting from forced degradation.

• Characterization And Relative Quantification Of mRNA 5’-Capping

  Review the development of an LC-MS method for the reliable identification and relative quantification of different mRNA capping structures.

• Identifying Oxidative Impurities In LNP Formulation Lipids

  A test conducts on a novel fragmentation mode for the detailed characterization of lipids, reveals information that can be used to determine drug efficacy and safety from formulated LNPs.

• Comprehensive Peptide Mapping Of Protein Therapeutics

  Explore how the peptide mapping workflows templates provided by a software designed for the characterization of biotherapeutic digests alongside data visualization and interrogation.

• Transforming Analytics To Optimize Cell Line Development

  For cell line development, much of a workflow’s success hinges on how much analytical data a team can get – and how quickly – to inform their process.