This data sheet provides information on the 50 L Thermo Scientific™ HyPerforma™ DynaDrive™ Single-Use Bioreactor (S.U.B.) system, which includes the tank and standard S.U.B. BPC. The BPC utilizes the novel impeller configuration and dual-sparger design (enhanced drilled- hole sparger (DHS) and porous-frit sparger) as well as a cross-flow sparger when operating at 10 L liquid volume or less. All sparger designs have been rigorously tested to provide high kLa values and optimal CO2 stripping for improved pH control and decreased foaming.
The HyPerforma DynaDrive S.U.B. is our latest advancement in S.U.B. technology; it offers better performance and is scalable to larger volumes than previous bioreactors. The complete HyPerforma DynaDrive S.U.B. system consists of a 50 L bioreactor tank and DynaDrive S.U.B. BioProcess Container (BPC). This cube-shaped tank and unique stirred-tank design utilizes a novel drive train with multiple impellers. The mixing capability of the bioreactor is superior, which enables optimal mixing capability and mass transfer performance. The newly designed tank shape allows for mixing at very low volumes and has a turndown ratio of 10:1.