Application Note

HyPerforma Glass Bioreactor For Fermentation Of Saccharomyces Cerevisiae

By Nadezda Perepelitsa, Stephan C. Kaiser, and Dieter Eibl

Fig 1
Figure 1. The HyPerforma Glass Bioreactor, and HyPerforma G3Lab Controller with TruBio software.

This application note describes the cultivation of Saccharomyces cerevisiae in the Thermo Scientific™ HyPerforma™ Glass Bioreactor with a maximum working volume of 2.0 L. Using the chemically defined medium D, it was possible to produce up to 5.33 g/L of dry biomass using 40 g/L glucose. The cells were grown under aerobic conditions with a specific growth rate of up to 0.4/hr and a yield coefficient for the biomass of 0.13 gCDW/gGluc.

VIEW THE APPLICATION NOTE!

Get unlimited access to:
Trend and Thought Leadership Articles
Case Studies & White Papers
Extensive Product Database
Members-Only Premium Content
Welcome Back! Please Log In to Continue. X

Enter your credentials below to log in. Not yet a member of Pharmaceutical Online? Subscribe today.

Subscribe to Pharmaceutical Online X

Please enter your email address and create a password to access the full content, Or log in to your account to continue.

or

Subscribe to Pharmaceutical Online

Please tell us more about you so that we can customize our newsletters to your specific interests:

Thermo Fisher Scientific