Key Considerations When Filling Dual Chamber Syringes Within An Aseptic Isolator

By Giel van Veen

In the medical and healthcare industry, there is an increasing demand for prefilled syringes as a drug delivery format. It offers various advantages such as ease of drug handling, high dosing accuracy, and maintaining drug stability. This form of drug delivery system minimizes potential contamination from bacteria, which further ensures patient safety.

Dual chamber syringes combine the storage of a powder and a diluent into one primary packaging. By simply exerting pressure on the plunger, the liquid of the lower chamber is forced into the chamber that houses the drug substance, allowing the content of both chambers to be mixed and easily administered. This simplifies the administration process and ensures a longer shelf life of the drug substance, which provides great advantages compared with conventional vial drug delivery systems.

Learn about the challenges of the DCS filling manufacturing market and how to overcome them.