Key Considerations When Transferring Drug Products Into Barrier Systems

By Matthias Angelmaier

When transferring products and materials into barrier systems, there are many things to consider. It begins with categorizing the pharmaceutical product and defining the aseptic environment along with asking a baseline of initial questions including how a product is categorized, what processes and procedures are commonly used, and what the major challenges in product and component supply are.

There are numerous considerations to be taken into account when planning aseptic production. Often, shortcomings are only revealed at a very late planning stage or – in the worst case – during production. Older installations without sufficient barrier or lower categorization are increasingly being upgraded in the direction of at least RABS, as worldwide authorities regulations increasingly demand this. Therefore, it is highly recommended that strong and experienced partners who can provide comprehensive advice based on decades of experience be relied upon during facility and transfer systems design.

Read to learn about maintaining aseptic barriers, the different needs for different packaging types, and more.