mAb Up- And Downstream Process Intensification Strategies

This webinar explores the intensification of monoclonal antibody (mAb) production processes to reduce manufacturing time and costs. Experts will discuss upstream and downstream process improvements, including continuous perfusion for increased upstream performance, the use of ultrahigh cell density banks to eliminate seed train steps, and the implementation of advanced chromatography tools for streamlined purification.

Specifically, the webinar will cover:

Upstream intensification: Continuous perfusion and ultrahigh cell density banks for reduced seed train steps.

Downstream intensification: High-capacity protein A resins, flowthrough polishing with mixed-mode and hydrophobic interaction chromatography.

Attendees will gain insights into the latest strategies for efficient and cost-effective mAb production. Featured speakers include Maren Grün, Vivian Ott, and Matthew Zustiak, who will discuss upstream process intensification, and Manuel Matos, who will focus on downstream purification advancements.