Application Note

Mixing And Blending Recommendations For Sterile Ingredients

By Matt Smith

sterile cleanroom protective gear

To respond to legislative and customer requirements, the pharmaceutical industry is having to demand ever increasing standards of hygienic construction in process equipment. This is applicable to all forms of pharmaceutical products - ointments, suspensions, syrups, etc. Products manufactured under sterile or cleanroom conditions - for example injectables and vaccines - present different challenges, especially regarding product sterilization. For these products, mixing would normally take place before sterilization but there are instances where post-production sterilization is impossible for technical reasons, placing further restrictions on the mixing process.

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