Mold In Cleanrooms: A Persistent Threat And The Case For Proactive Bio-Decontamination

Mold persistence in controlled environments often stems from what cannot be seen. While surface cleaning addresses immediate contamination, spores frequently colonize hard-to-reach infrastructure, such as HVAC ducting and spaces adjacent to high-humidity zones like walk-in incubators. True eradication requires looking beyond obvious contact surfaces to identify root causes hidden within the facility's geometry.

A recent scenario involving a vaccine manufacturer highlights the limitations of localized intervention. Despite achieving a 6-log sporicidal kill inside incubators, contamination recurred until the bio-decontamination scope was expanded to include difficult-to-access adjacent areas. Moving from reactive measures to a scheduled, systems-level approach, in this case, utilizing hydrogen peroxide vapor to penetrate complex geometries, ensures that critical manufacturing processes remain uninterrupted and compliant. Access the case study to understand how expanding decontamination boundaries can transform a recurring risk into a managed process.