24-Month Post-Gamma Qualification Of Single- Use pH Sensors In Single-Use Bioreactor, Mixer, And Fermentor Equipment

By Josh Adams and Nephi Jones, Thermo Fisher Scientific

The implementation of new process analytic tools is consistent with Thermo Fisher Scientific’s continuous improvement process and open architecture support. Hamilton Company’s OneFerm™ pH VP 70 sensor (HC part # 238999-4955 and TFS part # SV21484.01) is a single-use glass electrode that provides an additional option for customers wishing to implement single-use pH sensing capabilities in the S.U.B., S.U.F, and S.U.M.

The OneFerm™ probes were tested against manufacturer specifications to ensure a robust option even after 24 months of dry storage post-irradiation.

The purpose of this scientific poster is to determine if Hamilton OneFerm™ sensors have sufficient gamma stability, low drift, long shelf life, and ease of integration in Thermo Scientific™ HyPerforma™ Single-Use Bioreactors (S.U.B.), HyPerforma™ Single-Use Fermentors (S.U.F.), and HyPerforma™ and imPULSE™ Single-Use Mixers (S.U.M.).