The Natoli NP-RD30 rotary tablet press is included as part of a new research and training facility for Diosna Dierks & Söhne GmbH.
The Diosna Dierks & Söhne GmbH recently opened the “Diosna ProcessLab” located in Osnabrück, Germany. The Diosna ProcessLab was completed in April 2020 and offers research and formulation trials as well as virtual and in-person training classes. The Diosna ProcessLab offers an overview of the different system options and various possibilities for experimental implementation.
One of the systems included in the Diosna ProcessLab is the Natoli NP-RD30 (Pictured below). The NP-RD30 is designed to help solve formulation and scale-up challenges. The multi-functional rotary tablet press replicates the design and functionality of a full-scale production press with the analytical capabilities of an R&D machine.
The NP-RD30 helps to get products to market faster with the data acquisition, analysis, and scalability features included in its user-friendly interface. The NP-RD30 is 21 CFR Part 11 compliant. It comes with an intuitive 21” HMI touchscreen and USB port for data transfer. Rolling casters allow for easy mobility of the machine. The NP-RD30 is equipped with an integrated duel vacuum system, a built-in calibration tool, upper and lower punch seals, powder recirculation system, and self-adjusting lower punch retainers with an exclusive push button feature.
An optimized fast-fill cam design creates a vacuum to assist in die filling for more consistent tablet weights. The NP-RD30 is designed with same diameter pre- and main compression rollers, independent overload, ejection, and take-off force monitoring. While designed to meet the needs of research and development, the NP-RD30 can be used as a small batch production press with efficient and dependable standard batch reporting.
The NP-RD30 will be used to help enable the complete production of tablets for seminars, training, and more. The Natoli NP-RD30 completes the manufacturing process chain at the Diosna ProcessLab that starts with powder mixing, granulation, final blending, tableting (completed with the NP-RD30), and finally, coating of the tablets. Customers who perform formulation trials at Diosna ProcessLab, are able to compress the granules to tablets, getting the opportunity to handle and analyze the quality of the final tablet with all its physical and chemical characteristics.
Natoli staff was on site to complete set-up of the NP-RD30. Sebastian Boos, Natoli Representative (Germany) and Hans Eirik, Natoli Service Technician (Europe) worked with the Managing Director, Henrik Oevermann, the Head of the ProcessLab, Michael Benjamin, and the Area Sales Manager, Andreas Znidar to ensure installation was a success.
The first seminar in the new Diosna ProcessLab, “PTS-Seminar: Intensive Training Wet Granulation”, is planned for October 28-29, 2020 depending on availability of the Diosna ProcessLab due to current global circumstances. The number of attendees has been reduced to provide a safe environment in accordance with the Good Manufacturing Practice (GMP) standards with the World Health Organization (WHO). The Diosna ProcessLab and the equipment was also built according to GMP standards.
About Natoli Engineering Company
The undisputed global leader in tablet compression tooling manufacturing, Natoli Engineering Company has served the pharmaceutical, nutritional, confectionery, and veterinary industries for more than 45 years. In addition to encapsulation products, Natoli also offers tablet presses, tablet press replacement parts, tooling and press refurbishing services, analytical inspection equipment, technical training courses, and the most comprehensive tablet compression accessories catalog in the industry. Natoli AIM™ R&D and Operating Control Systems Software facilitates and speeds tablet and capsule research and development and provides powerful data and reporting capabilities through production. For more information, visit www.natoli.com.
About Diosna Dierks & Söhne GmbH
With more than 135 years of experience, Diosna Dierks & Söhne GmbH operates successfully in two business units; Machines for the food industry and machines for the chemical and pharmaceutical industry. The focus in the food industry is the Bakery division which offers solutions for various ways of preparing dough. The second business unit main segments are mixing, granulating, coating, and drying. From small laboratory mixers to complete production plants, this business unit provides solutions for the Chemical, Pharmaceutical, Cosmetic, and Food industries. Diosna Dierks & Söhne GmbH is one of the biggest suppliers for machines for food, chemical, and pharmaceutical industry, the inventor of the High-shear mixers, and the expert in granulation technology. They are a reliable and competent partner for best kneading and mixing technologies. For more information, visit https://www.diosna.com/.