Natoli Engineering Company, Inc., is the recognized global leader in tablet press tooling manufacturing. Founded on the uncompromising principle to manufacture and deliver only the highest quality tablet compression tooling, presses and replacement parts at a fair price with exceptional customer service, Natoli has been at the forefront of the tablet compression industry for over 40 years. Our state-of-the-art manufacturing facilities, award-winning engineering team and dedicated production crew enables us to offer clients competitive pricing without compromising our high standards of customer service. Trust in Natoli – our staff has the industry knowledge and expertise to understand and meet your exact requirements and requests.
Natoli Engineering Company, Inc.
28 Research Park Circle
St. Charles, MO 63304
Contact: Dale Natoli
This paper describes how to understand punch length, how to measure it correctly, and how wear affects length and tablet consistency. It also addresses the importance of specifying cup-depth tolerances.
All formulators need a methodology that gives them reliable and useful information to identify problems before tablet manufacturing begins.
Avoid production quality-related issues by understanding and knowing how to identify the most common causes of punch tip edge wear.
Tooling is a significant investment for companies. Individual punches and dies may represent a small portion of production costs in relation to the purchase and maintenance of the equipment, such as fluid bed dryers and tablet presses.
When scaling a new drug formulation from the development side of R&D into manufacturing, there is often a reality check with respect to process scale- up and performance of the formulation at production levels. By Chuck Kettler, Director, Natoli Scientific of Natoli Engineering Company, Inc.
Problems with capping/lamination and sticking/ picking are often first realized when a formulation is introduced to a level of compression required to supply market demand.
Providing support in all aspects of the tablet compression process should be expected from your tooling and tablet press partner.
Tablet land is beneficial to add strength and durability to the punch tip. But, this hand land may be perceived as making it more difficult to coat the tablet.
In the design and manufacture of tablet compression tooling, nothing is more important than the quality of the materials being used.
It's no surprise that in today's struggling economy, companies are facing budget cuts across the board. In an effort to help our customers address these challenges, we put together this list of 8 Ways to Reduce Tablet Manufacturing Costs.
Anyone who has experienced capping or lamination during tablet production knows the frustration that comes from trying to diagnose the issue. This article discusses a possible cause and several solutions.
Multi-tip tooling is available in two common configurations: assembly (or multi-piece) and solid. When choosing the configuration, consider the tool type, tablet size, and the number of tips per punch. By Dale Natoli, Vice President
Tablet compression tooling, commonly referred to as punches and dies, is probably the most misunderstood element of the tablet manufacturing process. Tooling is responsible for the tablet shape and face configurations, and is also an integral factor for an efficient tablet operation. By Dale Natoli, Vice President
If your business is in the tablet compression industry, then you are most likely using tablet compression tooling of the standard "B" and or "D" configuration, regardless of the country you are in. Tablet compression tooling is often referred to as tooling, or more commonly, punches and dies. By Dale Natoli
Choosing the right tooling can increase tablet output, decrease waste and ultimately determine the success of a product launch.
Clean punches and dies are essential to maintaining the integrity and efficiency of your tooling investment, as well as the quality of your product. Ultrasonic cleaning has long been considered the most effective, nondestructive way to clean tools.
Inspecting tooling and press components for wear or defects could be the most important step in improving tablet quality.
First impressions are everything. This is especially true for pharmaceutical, nutritional and confectionery tablets. Discriminating consumers may decide if they will be repeat customers based on a tablet’s appearance and their experience with it. This article discusses the limitations of the flat faced bevel edge and the benefits of a flat faced radius edge tablet design.