Residence Time Of Powders In Tablet Compression

Knowing how formulation moves through a tablet process is invaluable in optimizing the process for the greatest tablet quality and production. Residence time refers to the total time a particle or batch of material spends in a particular process or piece of equipment. In tablet compression, this refers to the time formulation spends in a hopper or a feeder. A good place to start is looking at the flow rate of the formulation since residence time is proportional to the flow rate at steady-state operation. To calculate the formulation’s flow rate through a tablet press, you will need: bulk density, tablet weight, press output (tablets per minute), and yield percentage (%).