Product/Service

Quick-Release Pharmaceutical Tablet Tooling

Source: Natoli Engineering Company, Inc.

Quick-Release Pharmaceutical Tablet Tooling

Natoli Quick-Release Tablet Tooling allows researchers to test different dwell times during the tablet R&D process without the expense of buying several different sets of tools or the time needed to change complete sets of tooling or turret speed.

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Prior to the introduction of Natoli Quick-Release Tooling, researchers had to buy several different sets of tooling with different punch head configurations to change the dwell time on an R&D press. In addition to not having to incur this expense, Natoli Quick-Release Tooling eliminates the time and labor required to remove and replace multiple sets of tooling during R&D.

Natoli Quick-Release Tooling allows R&D teams to evaluate dwell times with respect to both turret speed and head flat profile by quickly and easily changing the punch heads, which are a critical component of dwell time. This permits a much more detailed analysis of a formulation's compressibility as well as greater troubleshooting capacity in the early development stages.

Being able to use different head profiles provides the unique opportunity to determine the ideal dwell time for a given formulation or product. The ability to achieve a specific dwell time is invaluable for continuous manufacturing because as powder is fed at a specific rate, there is little ability to adjust turret speed to achieve the ideal dwell time or resolve related tablet defect issues. By changing the head – which can be done simply by squeezing the tabs on the side of the barrel, removing the head, and snapping a different head into the punch barrel – it is possible to determine the ideal compression profile for a product while keeping the turret speed at the specific requirement relative to powder feed and desired tablet output.

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Natoli Engineering Company, Inc.