Optimizing Gastric Resistance In Complex Oral Drug Products With Novel, Functional, Ready-To-Fill Capsules

By Ashish Guha, Bettina Hoelzer, Vinay Jain, Kamlesh Oza and Peter Niepoth, Evonik

Functional capsules can improve a targeted drug delivery strategy and allow the use of more sensitive active molecules. Evonik’s newly launched platform of functional ready-to-fill HPMC (hydroxypropyl methyl cellulose) capsules are completely free from animal-derived products. EUDRACAP^TM capsules help to optimize the release profile of complex oral drug products, protect even the most sensitive active ingredients, and speed up time to market.

Developing a delayed release formulation of acid sensitive actives that can be used in a solid dosage form such as tablets, pellets or capsules can be costly. Usually several stages are involved starting from R&D development to scale up and validation steps. All these stages require significant investment of time and money. Using a ready-to-fill functional capsule can save costs, reduce time to market, and boost performance of oral drug delivery products.