Prioritizing Product Integrity: Innovative Liquid Handling Solutions For Bulk Drug Substance Management

By Jarv Campbell, Subject Matter Expert, Bioprocess Division, Thermo Fisher Scientific

Liquid handling plays a critical role in biopharmaceutical manufacturing. Ensuring that bulk drug substances are stored, handled, transported, and treated properly is of paramount importance to guarantee their integrity and safety. This is true throughout the pharmaceutical pipeline, but becomes even more pressing as drug products reach the manufacturing stages.

The further bulk drug substances progress along a manufacturing workflow, the more valuable they become—and the more damaging it would be to lose them. Manufacturers need containment technologies that enable them to optimize and streamline their bulk drug substance management workflows.

Such technologies must eliminate the risk of contamination and conform to stringent cleanliness standards to facilitate compliance and, crucially, protect the integrity of the product. Innovative technologies—both single use and rigid—bring flexibility and efficiency for biopharmaceutical manufacturers of all sizes, increasing their ability to develop new therapies and fast-tracking the process of bringing a new drug to market.