Production Scale Bioprocessing Solutions

Thermo Scientific Production Scale Solutions

Flexible, reliable, and configurable bioprocessing solutions
The Thermo Scientific™ HyPerforma™ G3Lite™ Controller is an open architecture control system that can be integrated with any single-use bioreactor such as the Thermo Scientific™ HyPerforma™ Single-Use Bioreactor (S.U.B.) (Available in sizes ranging from 50 L to 2,000 L). The system consists of a control tower that leverages intelligent transmitters, mass flow controllers (MFCs), pumps, sensors, and Thermo Scientific™ TruBio™ software that facilitates easy, reliable, and repeatable process development and commercial cell culture processes. HyPerforma G3Lite Controllers are fully self-contained, movable units that can be operated as stand-alone (for 1 vessel) or networked for multiple vessels. They are engineered to optimize capital cost for use in non-GMP and cGMP-certified production facilities.

HyPerforma G3Lite Controller Key Features

  • Stand-alone or networked (for multiple vessels)— enabled by distributed control system (DCS)
  • Includes up to six MFCs with air, O2, NS, CO2 for drilled-hole spargers (DHS); air for frit or open pipe spargers; air for overlays
  • Probe configuration options—flexibility to connect electrochemical, single-use, or both for pH and dissolved oxygen (DO) measurements
  • Foam level, load cell, and TruTorrTM II pressure transmitters included in controller
  • Scalability—transfer any process from 50 L to 2,000 L
  • Modularity—predefined configurations available for 50, 100, 250, 500, 1,000, and 2,000 L bioreactors
  • Scales and pumps available for multifeed purpose, including four peristaltic pumps for acid, alkali, antifoam, and feed
  • Includes vent filter heater controller
  • Touchscreen interface for easy data entry and control when necessary
  • Temperature control unit (TCU) integration options available for implementing a temperature control strategy


  • Open architecture capabilities to integrate and communicate with vessels from other suppliers
  • Return on investment (ROI)—increase productivity and minimize downtime