Rapid Separation Of Circular RNA Using A High-Resolution mRNA Analysis Kit

By Mario A. Pulido, Peter Holper, Jane Luo, Paul Baker, Tingting Li and Sahana Mollah, SCIEX, USA

Achieve high-resolution separation of circular RNA (circRNA) species from linear RNA products using the BioPhase 8800 system and the RNA 9000 Purity & Integrity kit. The BioPhase 8800 is a pre-assembled, bare-fused silica multi-capillary cartridge and a high-throughput electrophoresis system. This kit and approach can also detected complex species, such as RNA concatemers, low-level impurities and fragmentation, by utilizing capillary gel electrophoresis with a laser-induced fluorescence detector (CGE-LIF).

Find out how you can utilize the RNA 9000 Purity & Integrity kit's key features, to detect impurities present at 0.1% of the main product.