Application Note

Rapid Thermal Stability Screening Of High Concentration Biologic Drugs

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Testing the thermal stability of biotherapeutics is critical for ensuring product quality and supporting the regulatory approval of biologic drugs. The TA Instruments™ RS-DSC (Rapid Screening-Differential Scanning Calorimeter) offers a solution for analyzing up to 24 samples at once. Additionally, it allows for the evaluation of protein drug candidates at high concentrations using low-volume disposable microfluidic chips. This application note presents data showcasing the effectiveness of the TA Instruments RS-DSC and evaluates its detection limits and the range of concentrations suitable for DSC analysis.

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